Protein Info for Rru_A2661 in Rhodospirillum rubrum S1H

Annotation: Putative diguanylate cyclase (GGDEF domain) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 644 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 373 to 393 (21 residues), see Phobius details PF00672: HAMP" amino acids 393 to 450 (58 residues), 37.6 bits, see alignment 2.3e-13 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 475 to 638 (164 residues), 140.7 bits, see alignment E=1.8e-45 PF00990: GGDEF" amino acids 478 to 634 (157 residues), 134.3 bits, see alignment E=3.4e-43

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2661)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RQY7 at UniProt or InterPro

Protein Sequence (644 amino acids)

>Rru_A2661 Putative diguanylate cyclase (GGDEF domain) (NCBI) (Rhodospirillum rubrum S1H)
MGAEGASLDDADTPSMAAQAAARLSVLGLLIVGLVSLVGYFFVFDWDKTQALERLSDFLV
QRRALENTLFDEAQRNGERFHALFLDDYHGAPPLDEAEFGRYFQQDGTDGPWRTRPEFYH
GLRDREGGLIAGVSGFIAAGRGAVAPDHARRLVVSMRLLGRLGPAWSGAFANSTISTPEN
GSLLYWPGVPWGLEAAADLRPAEGSVIASTLVEHNPQRRPVWTALYHDLTADAWTVTYQR
PIDEDGRHLVTFGHDLLLNAMLNRLASDHPPGASSFLLGADGSLIAHAGSEERMAHIGTQ
IDLETLGDPALLRRYRLLVAAVGQRGGDGVWMVEDREDHAWLAATELSGPGWWYVISYPK
EVIADRARRAANQVVIGGVVLSFLLVAMVQLVMRRRVARPLAQLARAAGAVGTGQTALVA
SGGLDLPIGERNEIGVLARAFREMAMRVRDHEVILEREIANRTGALEEANRRLHSLSETD
GLTGLFNRRALDRDLAGHCALARGGGGAVALIMVDIDYFKAYNDAEGHLAGDDALRKVAQ
RLLSILRPGDTIYRYGGEEMAVLIGGAGADGAVGVARRIVDEVAALAIPHPASPFGVITL
SAGLAVLRGEATLPKTLISRADEQLYAAKRGGRNVLVVAPTDPA