Protein Info for Rru_A2606 in Rhodospirillum rubrum S1H

Annotation: Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 664 transmembrane" amino acids 15 to 40 (26 residues), see Phobius details amino acids 336 to 360 (25 residues), see Phobius details PF08269: dCache_2" amino acids 191 to 322 (132 residues), 76.9 bits, see alignment E=3.1e-25 PF17200: sCache_2" amino acids 221 to 325 (105 residues), 44.2 bits, see alignment E=3.9e-15 PF00512: HisKA" amino acids 432 to 496 (65 residues), 33 bits, see alignment E=9.8e-12 PF02518: HATPase_c" amino acids 540 to 649 (110 residues), 91.3 bits, see alignment E=1.1e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2606)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RR42 at UniProt or InterPro

Protein Sequence (664 amino acids)

>Rru_A2606 Periplasmic Sensor Signal Transduction Histidine Kinase (NCBI) (Rhodospirillum rubrum S1H)
MIKVRRDHAPPTRSLIQVLSLTTVGASLIFLLMLSVLWGIGRAQDMAISADILRSSLLIE
RQQALRGTVERALRVVGGLRAQAERERLDALKAEVIQARSLANHLLNRYGKAPSSPLSAS
PPRPGAAGAPGLIANALQAFDAGAEDRGLFVLDAAGGSPAGSPPPSAALVAELWALARGG
GGYLGSGEGAARRIYYVEAFAPFEWVIGSWRLVEAGEAALQRAALETLAAENGGVGDIFV
GTWEGVALLGPGQGRDQRELTDSDGVKPVALLIDQARSGRPGFVEYRAPYGSRVNARKLS
YVAAIADWRWYVGTGVMLDDIDALANNRLGVMRTALAWEVLGGIALIGLAGLTITWGLLR
VRRRLEASHRRFLAFLDEAAQGRGEIDPAAMEFLEYRDLAASANRMVEQRRDALSRLAER
GVELQRSNRELERFAFIASHDLQEPLRSIAGFIQLIERRLGPDIDPEVAEFFSFVVGGAG
RMRDQIEGLLEYSRLDRAQLERTVVVLDEVVAEVIAELEPQIAAAGACVRVEVLPVVSAD
RGQLRLLFTHLLDNALKFRNPDRPPELRISALRDVDGCWRISVGDNGIGIAEAYHAQVFD
LFRRLHSAGTYAGTGLGLAVCRRIVERHGGDIRLRSVPGRGTTVSFTLMAPADGPHAAGW
NRAH