Protein Info for Rru_A2549 in Rhodospirillum rubrum S1H

Annotation: HAD-superfamily hydrolase subfamily IIB (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 297 TIGR00685: trehalose-phosphatase" amino acids 39 to 295 (257 residues), 133.5 bits, see alignment E=1.2e-42 TIGR01484: HAD hydrolase, family IIB" amino acids 43 to 255 (213 residues), 63.1 bits, see alignment E=3.9e-21 PF02358: Trehalose_PPase" amino acids 44 to 281 (238 residues), 132.9 bits, see alignment E=5e-43

Best Hits

KEGG orthology group: K01087, trehalose-phosphatase [EC: 3.1.3.12] (inferred from 100% identity to rru:Rru_A2549)

Predicted SEED Role

"Trehalose-6-phosphate phosphatase (EC 3.1.3.12)" in subsystem Trehalose Biosynthesis (EC 3.1.3.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RR96 at UniProt or InterPro

Protein Sequence (297 amino acids)

>Rru_A2549 HAD-superfamily hydrolase subfamily IIB (NCBI) (Rhodospirillum rubrum S1H)
MTASSLRSPQAPKNQAKPIEQLIPILDETASFLAALKGRTPVVFLDFDGTLAPIAERPEA
VVFSAARREAVRKLAGKLPVAIVSGRDRADVEKQVGLPGLTYAGGHGFDIRLAPSGSASE
VAPDDADPLAAELDGGLAGLVERLDAMEAALHAGLDGIAGALIERKRFSVAAHDRMVAPA
DRPAFAAALEAARRDLRGLREKAGKRLVEFLPDIDWDKGKAVLHLRRALGVDGEGYVAVF
FGDDLTDEDAFRVLPEIDGIGVLVAGADEDGRGRTSHAFFRVADPDGVCRLLNDMVA