Protein Info for Rru_A2518 in Rhodospirillum rubrum S1H

Annotation: Multiple antibiotic resistance (MarC)-related proteins (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 211 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 40 to 60 (21 residues), see Phobius details amino acids 71 to 91 (21 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details amino acids 184 to 204 (21 residues), see Phobius details PF01914: MarC" amino acids 5 to 207 (203 residues), 164.7 bits, see alignment E=9.5e-53 TIGR00427: membrane protein, MarC family" amino acids 6 to 203 (198 residues), 145.6 bits, see alignment E=8.2e-47

Best Hits

KEGG orthology group: K05595, multiple antibiotic resistance protein (inferred from 100% identity to rru:Rru_A2518)

Predicted SEED Role

"Membrane protein, MarC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRC7 at UniProt or InterPro

Protein Sequence (211 amino acids)

>Rru_A2518 Multiple antibiotic resistance (MarC)-related proteins (NCBI) (Rhodospirillum rubrum S1H)
MIDSLLSQITTLLVLVDPLGLLAIFVGLTAGRPAAYRRQVAIKGTLLATFVLVAFAVAGG
KFLHLLGIDISAFRIAGGLMLLVLAHEMIFAKRTIRRNESAKAMDKEMGGETSDPSVFPL
AIPLIAGPGAITAVLLFSRESDGTAIGLMWVIVAILAVTLPTLALLLTAGAVQRMLGETL
THTLDRLLGIILGALAVQFIISGAKEALGAL