Protein Info for Rru_A2499 in Rhodospirillum rubrum S1H

Annotation: ABC-2 transporter component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 transmembrane" amino acids 36 to 56 (21 residues), see Phobius details amino acids 73 to 95 (23 residues), see Phobius details amino acids 115 to 143 (29 residues), see Phobius details amino acids 149 to 174 (26 residues), see Phobius details amino acids 183 to 204 (22 residues), see Phobius details amino acids 243 to 263 (21 residues), see Phobius details PF01061: ABC2_membrane" amino acids 21 to 230 (210 residues), 90.1 bits, see alignment E=1.6e-29 PF12698: ABC2_membrane_3" amino acids 65 to 256 (192 residues), 61.2 bits, see alignment E=9.6e-21

Best Hits

KEGG orthology group: K09686, antibiotic transport system permease protein (inferred from 100% identity to rru:Rru_A2499)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRE6 at UniProt or InterPro

Protein Sequence (276 amino acids)

>Rru_A2499 ABC-2 transporter component (NCBI) (Rhodospirillum rubrum S1H)
MTALSTPLSDPPRVSVPSVAFALAKREFTRFVRQPARLAGSIGQPLLFWLVLGSGLSPSF
RPTGMAAMSYTEYFYPGMLLMMVLFASVFSTITVIEDRDQGFLQGVLVAPVSRLAIVLGK
VGGAAAIALFQSIVLLCAAPVLGFSTGPLGYLLILVTLTLLSLGFTGLGFLTAWGMASTS
GFHAVMMLVLMPLWFLSGALFPVQGVPAVLEGLMMINPVTHGMTILRAPFYEAPGALLSD
GSYLGSLAVVALWVVLALGASAWRVGRRERGAPSPS