Protein Info for Rru_A2474 in Rhodospirillum rubrum S1H

Annotation: extracellular solute-binding protein, family 5 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 signal peptide" amino acids 1 to 16 (16 residues), see Phobius details PF00496: SBP_bac_5" amino acids 59 to 423 (365 residues), 185.1 bits, see alignment E=1.1e-58

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 100% identity to rru:Rru_A2474)

Predicted SEED Role

"Dipeptide-binding ABC transporter, periplasmic substrate-binding component (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) or Bacterial Chemotaxis (TC 3.A.1.5.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRH1 at UniProt or InterPro

Protein Sequence (525 amino acids)

>Rru_A2474 extracellular solute-binding protein, family 5 (NCBI) (Rhodospirillum rubrum S1H)
MTAWIVLTAPAASTAAEFRWTAAQGPATLEPQSPEALADPGVLGDVYETLIGRDSDLDLE
PALATAWQAVTDLRWRVTLRRGVRFHDGAAFTADDVVASLERASARGGGLAEALAPVRRV
RRVDDTTVDLYTQTPTPDLPQRLALIRILDDGWIARADPAMPANGTGPFRVDRFTPGGAV
TLVANGDWWGRTIPADPLGTTAPPAPRLERATLIPAARPADRLRLLLEGKVDLALDLPPA
VVPPLAATPGLRALVIGGTRTVMLGMDQRPPPLGAARGQGSPFRDRLLREAVLRAVDMTD
IDQRLFANQATPAALIAGPMIAGVPAAADIRPAADPDRARALLAEAGVGPAGVSVTLDCP
LGFFLNDGALCDAIATSLSEVGIHTAVATRLAENHFPRVLRGESRFFLTGYQPLTLDILD
PLRALAACPPTDGSPKDGFGQANGAGYCDPSVDRLIRRLADEMIPARQSALAAEIVLKLR
DDVVYVPLHQEPVIWGARADIGLRQRADGVLDLRWVSPAPVPQGR