Protein Info for Rru_A2443 in Rhodospirillum rubrum S1H

Annotation: HipA protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 TIGR03071: HipA N-terminal domain" amino acids 10 to 109 (100 residues), 88.4 bits, see alignment E=1.5e-29 PF13657: Couple_hipA" amino acids 10 to 110 (101 residues), 97.8 bits, see alignment E=4.6e-32 PF07804: HipA_C" amino acids 154 to 400 (247 residues), 171.1 bits, see alignment E=2.8e-54

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 100% identity to rru:Rru_A2443)

Predicted SEED Role

"HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRK2 at UniProt or InterPro

Protein Sequence (435 amino acids)

>Rru_A2443 HipA protein (NCBI) (Rhodospirillum rubrum S1H)
MPRPHQEPPLAVFLNSRLVGRLNRTARGAIDFQYDSSWLEWDRALPISLSLPLREDRYSG
AAVNAVLENLLPDSALIRRRTAERVRAQGSDAYNLLAAIGRDCVGALQFLPDGEAPGTAG
TVDGIPVDDREIARLIKELSIAPLGLGEDIDFRISIAGAQEKTALLHWKDRWYKPCGTTA
TTHILKPRIGRLSNGLDLTSSVENEFLCLKVTAALGIPSADVALADFEDNRVLVVERFDR
HWTADDRLLRLPQEDCCQALGVPPTLKYQAEGGPGIEALLNLLKGSDVPKVDQTRFLKAT
VAFWLLGATDGHAKNFSVFLSSGGRFRMTPLYDVISAQPSADAGQIPRNRMKLAMFVGTN
RHYVIDTIMPRHFLQTAAAAGLGASLVEPVFADILATAPTALEDVMEALPKDFPRDIADS
ILGGFTERLRTLAKA