Protein Info for Rru_A2423 in Rhodospirillum rubrum S1H

Annotation: Aminotransferase, class I and II (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00155: Aminotran_1_2
  • amino acids 42 to 387 (346 residues), 183.3 bits, E=4.2e-58

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2423)

Predicted SEED Role

"Valine--pyruvate aminotransferase (EC 2.6.1.66)" in subsystem Alanine biosynthesis or Branched-Chain Amino Acid Biosynthesis or Pyruvate Alanine Serine Interconversions (EC 2.6.1.66)

MetaCyc Pathways

• superpathway of L-alanine biosynthesis (4/4 steps found)
• L-alanine biosynthesis I (2/2 steps found)

KEGG Metabolic Maps

• Valine, leucine and isoleucine biosynthesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.66

Sequence Analysis Tools

See Q2RRM2 at UniProt or InterPro

Protein Sequence (395 amino acids)

>Rru_A2423 Aminotransferase, class I and II (NCBI) (Rhodospirillum rubrum S1H)
MALFCVECGSMALKVARRGLIPPFIVMDVMRAAAEREATGAEVMHLEVGQPSTGLPEQAL
DEVARRLHSGPMGYTVALGLDALREAIALHYQRTQGVAVDPGRIIVTTGSSAGFILAFLA
AFEAGDRVGLAAPGYPAYRHILKALGCEPVILPTGPETRYQPTVAVLEEAGMDLDGLIVA
SPANPTGTVMPAADLKALVAYCGERGIRLISDEIYHGITYGEAALSTVGLAEHPVVVNSF
SKYFCMTGWRLGWLVLPPDLLRPVECLTQNLFISPPALSQYAGLAALRHHGAFEENIRRY
ARNRQILLDALPAAGFGAFAPADGAFYLYGDVSGLTDDSLGFCARMLAETGVAATPGLDF
DDARGAHFVRFSFSGATETIEKAARRLLEWKGGRG