Protein Info for Rru_A2413 in Rhodospirillum rubrum S1H

Annotation: Poly(R)-hydroxyalkanoic acid synthase, class I (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 598 TIGR01838: poly(R)-hydroxyalkanoic acid synthase, class I" amino acids 64 to 595 (532 residues), 784.6 bits, see alignment E=2e-240 PF07167: PhaC_N" amino acids 107 to 278 (172 residues), 276 bits, see alignment E=1.1e-86 PF00561: Abhydrolase_1" amino acids 282 to 522 (241 residues), 38.6 bits, see alignment E=9.7e-14

Best Hits

Swiss-Prot: 50% identical to PHAC_AZOC5: Poly(3-hydroxyalkanoate) polymerase subunit PhaC (phaC) from Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571)

KEGG orthology group: K03821, polyhydroxyalkanoate synthase [EC: 2.3.1.-] (inferred from 100% identity to rru:Rru_A2413)

Predicted SEED Role

"Polyhydroxyalkanoic acid synthase" in subsystem Polyhydroxybutyrate metabolism

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRN2 at UniProt or InterPro

Protein Sequence (598 amino acids)

>Rru_A2413 Poly(R)-hydroxyalkanoic acid synthase, class I (NCBI) (Rhodospirillum rubrum S1H)
MANQGSEKTPPDPARIGKTMADIAERSQKLVTDFMTRQATSPTGGMDDPMNIGQAFLDMT
RQMMSHPERLVEAQMSLWQDYLALWQTTALRMMGAEAHPVATPAQGDRRFKDEAWDNNEV
FDFIKQTYLLTARWMQGVVRDVDGMDRHTAEKVDFYTRQFVDAMAPSNFALTNPEVIRET
LDSGGENLVKGLEHLLHDLERGKGQLRISMTDESAFEVGVNVAATPGKVIARNSLMELLQ
YTPTTEQVHKRPLLIIPPWINKYYILDLRPKNSFIKWAIDQGHSVFVISWVNPEADLAAK
SFEDYMVEGPLAALDIIKTITGEDSVNAIGYCLGGTLLGCVLSYLEAKGQSDRIASATHF
TAMLDFSEPGELGIFIDDQSLTFLEGKMNKVGYLDGSEMATTFNMLRANDLIWSFVVNNY
LMGKDPFPFDLLYWNADSTRMPAAMHSFYLRKMYQENVLKDPGGVTLLGVPIDLRRNRTP
SYFVSAREDHIAPWRSTFAGAQLYSGPVRFVLAASGHIAGVVNPPSANKYCFWTNTKKAK
DAESWLEKASQTDGSWWTDWEAWVEKFTEGKVPARVPGDAGVPVLGDAPGDYVKVRAG