Protein Info for Rru_A2401 in Rhodospirillum rubrum S1H

Annotation: RuBisCO transcriptional regulator cbbR, LysR family (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 PF00126: HTH_1" amino acids 6 to 64 (59 residues), 72.8 bits, see alignment E=1.7e-24 PF03466: LysR_substrate" amino acids 90 to 293 (204 residues), 191.1 bits, see alignment E=1.6e-60

Best Hits

Swiss-Prot: 97% identical to CBBR_RHORU: HTH-type transcriptional regulator CbbR (cbbR) from Rhodospirillum rubrum

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2401)

Predicted SEED Role

"RuBisCO operon transcriptional regulator CbbR" in subsystem CO2 uptake, carboxysome

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRP4 at UniProt or InterPro

Protein Sequence (315 amino acids)

>Rru_A2401 RuBisCO transcriptional regulator cbbR, LysR family (NCBI) (Rhodospirillum rubrum S1H)
MRHATLRQMQIFDAVARHLSFSNAARELGLTQPAVSLQIKQIEALAGLPLFEQMGRVLLL
TQAGTILLGHVRTILAAVTDADKAMDALKGKRAGALRIGVVSTAKYFAPRLLSVFTAGYP
GVELGLTVANREQILGMIQENALDLFIMGRPPTEPAVRAERFAPNPMVMVAASDHPLVRR
KLTFHDLSGETFLMREPGSGTRILMEKLMTDHGVLPHRMIEMSSNETIKQAVMAGMGISL
LSRNTMSLELSVGRLVILDVEGLPIQRDWYVVIREGKHLLPVAEAMVAFLKARGEDLLSD
AIRTLPPRRNRHVSG