Protein Info for Rru_A2394 in Rhodospirillum rubrum S1H

Annotation: PepSY-associated TM helix (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 transmembrane" amino acids 13 to 40 (28 residues), see Phobius details amino acids 145 to 168 (24 residues), see Phobius details amino acids 200 to 222 (23 residues), see Phobius details amino acids 349 to 369 (21 residues), see Phobius details PF03929: PepSY_TM" amino acids 16 to 372 (357 residues), 178.7 bits, see alignment E=1.2e-56

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2394)

Predicted SEED Role

"FIG137594: Putative iron-regulated membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRQ1 at UniProt or InterPro

Protein Sequence (393 amino acids)

>Rru_A2394 PepSY-associated TM helix (NCBI) (Rhodospirillum rubrum S1H)
MDKTPRKSSGARLWFLVHSWMGLPLWAYVFFLCFTGTLASVSHEIMWLIDPEVRAGASGD
PAPASALIAAAEAAAPGSRALSVGWGADYMAATVRLGLENGLYAMAYVDPVSATLRGIGS
DNPLPVFLRALHGWLLSPWTGGYPWGWYLVAVMAIPLLGSVVTGMVVYKRFWRAFFTRPK
LRTGKGARVLLGDLHRLGGAWSLWFVLLIGVTGLWFLVQAAIVDLRGALDPGAPLVVIDR
ADLPKRAPGEHPPPAEVDAALAAAQATHAGGRVTALYFPGTAFDPIYAYGSGRVPLLSDV
TYVHPRTAEVLYSKKGGDSGPLGLASQILRPLHVGDFGGPGALGLAIKGVWFLFGLILSM
LIFSGMLIWSKRTVRATLEMRQGAKLGESPSHA