Protein Info for Rru_A2372 in Rhodospirillum rubrum S1H

Annotation: Sigma-24 (FecI) (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 39 to 198 (160 residues), 81.7 bits, see alignment E=2.4e-27 PF07638: Sigma70_ECF" amino acids 39 to 199 (161 residues), 23.9 bits, see alignment E=8.9e-09 PF04542: Sigma70_r2" amino acids 43 to 109 (67 residues), 53.3 bits, see alignment E=5e-18 PF08281: Sigma70_r4_2" amino acids 145 to 195 (51 residues), 46.5 bits, see alignment E=5.6e-16 PF04545: Sigma70_r4" amino acids 148 to 196 (49 residues), 29.4 bits, see alignment E=1.1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2372)

Predicted SEED Role

"FIG006045: Sigma factor, ECF subfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRS3 at UniProt or InterPro

Protein Sequence (214 amino acids)

>Rru_A2372 Sigma-24 (FecI) (NCBI) (Rhodospirillum rubrum S1H)
MLWPYRKCEAFAFQPREPLPGMGCSSRSVRRKRIVSAVLNAVFESYRRSLLGKLTRIVQD
RQIAEDLTQETYLRVRRAAESGPIDHIEAFLHRTARNLALDHLRRTKRRAGMGSSAVEDG
AIDDLADDRPSAEEALIERQTLTVLSEAMARLPQRARLVLTLSRVEDWPNTKIAAHLGIS
ERTVFNDLKLALGHCRDAMARVDKKENGARERLK