Protein Info for Rru_A2365 in Rhodospirillum rubrum S1H

Annotation: ATP-dependent helicase HrpB (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 860 TIGR01970: ATP-dependent helicase HrpB" amino acids 25 to 859 (835 residues), 991.1 bits, see alignment E=2.5e-302 PF00270: DEAD" amino acids 37 to 182 (146 residues), 33.5 bits, see alignment E=5.1e-12 PF00271: Helicase_C" amino acids 228 to 349 (122 residues), 43.2 bits, see alignment E=6.5e-15 PF08482: HrpB_C" amino acids 714 to 846 (133 residues), 173.2 bits, see alignment E=5.4e-55

Best Hits

KEGG orthology group: K03579, ATP-dependent helicase HrpB [EC: 3.6.4.13] (inferred from 100% identity to rru:Rru_A2365)

Predicted SEED Role

"ATP-dependent helicase HrpB"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRT0 at UniProt or InterPro

Protein Sequence (860 amino acids)

>Rru_A2365 ATP-dependent helicase HrpB (NCBI) (Rhodospirillum rubrum S1H)
MDPSRLLRTERERKAVMPPFSPGPLPIDPVLPALLEALASHGRAVLIAPPGAGKTTRVPP
ALLGALWLGGQKVVMLEPRRLATRAAARRMAFEAGEAVGQRFGFRVRGESRSGPLTRVEV
MTEGILTRRIQDDPELAGVGCVILDEFHERGLQGDLAFALLREIQGALRPDLRLLVMSAT
LDGAAIAALMDDAPVIESHGRAFPVTITHGERPAARDLGPAMARTILRALEDEPGSVLAF
LPGEREIAAVAGALARALPADTVLRPLYGALPPAEQDAAISPCPPGQRKVVLATDIAETS
LTIEGVRIVVDSGLRRSPRFDPQTGLSRLDTVRISQAGAEQRRGRAGRLEPGVCLRLWPE
AEHRALPAQETPEILAADLAPLALELARWGARDAAALCWPTPPPPGPLAQARDLLTSLGA
LEPAGGLSAHGAAMAALPLHPRLAHMVLAAKADGADDGALACLLAALLAERDILRPGPGA
ARDRDLTTRLEILIGQGRRAPAGQILRQPTLGAVRDEAARLRQLAGIAASASPEPARCGR
VLARAYPDRIAQARPGQPGRFLLSSGRGALIDVGDPLAAAAFLAVAEVDGAGSEARVFLA
APLDRADLEELFDEALRPCETVTWDPRAEAVVARVERRLGALVFESRDLPDRADPARTTP
AVCAGIRRLGLGCLPWTRETDRLRARVAFLHRVHSADDWPDLSDDALLASLADWLGPWLD
GITRRSAFARIDLMAALKALIGWRRLADLDRLAPAQMDVPSGVKVALDYEVPDGPVLAAR
VQQLFGLTRTPAVLDGGHPVLVHLLSPAGRPLQVTRDLAGFWKGSYAEVRKDMRGRYPKH
PWPEDPTGAEATNRVKPRGQ