Protein Info for Rru_A2351 in Rhodospirillum rubrum S1H

Annotation: Macrocin-O-methyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 PF05711: TylF" amino acids 15 to 294 (280 residues), 316.6 bits, see alignment E=1.2e-98 PF13578: Methyltransf_24" amino acids 127 to 259 (133 residues), 39.6 bits, see alignment E=8.5e-14

Best Hits

KEGG orthology group: K05303, macrocin O-methyltransferase [EC: 2.1.1.101] (inferred from 100% identity to rru:Rru_A2351)

Predicted SEED Role

"probable O-methyltransferase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.101

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRU4 at UniProt or InterPro

Protein Sequence (557 amino acids)

>Rru_A2351 Macrocin-O-methyltransferase (NCBI) (Rhodospirillum rubrum S1H)
MSLYPFLGSDASSADRYLRLIKRSLINDLYLELEAILHYLVLCRRRGEEADPGIIRDIAA
HRPDIVAHLRQARDEGGRVLWPETGGQVYDPHNISEHVHTMIGRRRLDHLHHCLDTLLAE
GIPGDLIEAGVWRGGATIFMRAHLAAHGVTDRAVWVADSFRGLPEPSVEEDRGYDLSQSL
EPILAISEERVKALFARYDLLDDQVLFLPGWFRETLPQAPIDKIALLRLDGDLYESTMDA
LLALYDKVAPGGFIIVDDCGAMPPCRRAVEDFRAERGISAPLERIDWTGMAWRKEGERLP
PLRSCSTAPFTEIKRPCPPISACAFYHTMETPDGLMTGQWDLRDTTDAYLGAVDFAGKTV
LEIGPASGYLTFHMERAGAAVTAVEPPLKRLWDIFPHQGVDRDAWRASFLQSIIRIRNSF
WYMHHHQGSKARLIETVPEAIPAEVGRFDIGVLAAILLHTRSPFSILESVAARVEETIIV
TDLYDCALGELPVMRLIPDPEGTAVDTWWSFSPRFFLQALACLGFPRAEVTIHHQRGPGD
SLFPMFTVVAHRDRSGR