Protein Info for Rru_A2302 in Rhodospirillum rubrum S1H

Annotation: Periplasmic binding protein/LacI transcriptional regulator (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 45 to 253 (209 residues), 24.8 bits, see alignment E=1.4e-09 PF13407: Peripla_BP_4" amino acids 46 to 302 (257 residues), 201.6 bits, see alignment E=1.8e-63

Best Hits

KEGG orthology group: K02058, simple sugar transport system substrate-binding protein (inferred from 100% identity to rru:Rru_A2302)

Predicted SEED Role

"Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RRZ3 at UniProt or InterPro

Protein Sequence (349 amino acids)

>Rru_A2302 Periplasmic binding protein/LacI transcriptional regulator (NCBI) (Rhodospirillum rubrum S1H)
MKKFLSSLVLAASLVAGPALAADAPVDVSQVPKGFSAKDVGKSYSIATVVKVDGIAWFDR
MREGAKQFGADTGHDTWMVGPSQADAAAQVQLVENLIAQGVDAICVVPFSVEALEPVLKK
ARDRGIVVIAHEASNITNADFVLEAFDNLAYGAKLMEVLGTYMKGEGKYVTTVGSLTSKS
QNEWIDGAIAYQKAHFPKMEQATGRLETYDDANTDYNKLKEVLTTYPDIKGILGGPMPTS
AGAGRLISERGLKDKLFFAGTGLVSVAGEYLSKGDIQYIQFWDPAVAAYAMNIVAVMALD
GKADQIKAGLNLGLPGYTSLTAPVAGKDKLLYGAGWVGVTKDNMEDYNF