Protein Info for Rru_A2297 in Rhodospirillum rubrum S1H

Annotation: Ribokinase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 4 to 294 (291 residues), 223.3 bits, E=4.6e-70
• TIGR02152: ribokinase
  • amino acids 5 to 301 (297 residues), 347.9 bits, E=2.5e-108
• PF08543: Phos_pyr_kin
  • amino acids 175 to 288 (114 residues), 45.2 bits, E=8.2e-16

Best Hits

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 100% identity to rru:Rru_A2297)

MetaCyc: 59% identical to deoxyribokinase monomer (Salmonella enterica enterica serovar Typhi)
RXN-14223 [EC: 2.7.1.229]

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• 2-deoxy-D-ribose degradation I (2/3 steps found)
• ribose phosphorylation (1/2 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.15 or 2.7.1.229

Sequence Analysis Tools

See Q2RRZ8 at UniProt or InterPro

Protein Sequence (309 amino acids)

>Rru_A2297 Ribokinase (NCBI) (Rhodospirillum rubrum S1H)
MSGRIAVVGSNMVDLITYVTRMPDKGETIEAPNFALGCGGKGANQAIAAARLGADVLMVT
RVGDDIFADNTIANFKANGIDTRFVRKVPGTPSGVAPIFVEQNGENSILIVKGANAHLSP
ADVEEAGEALKGCALILMQLEVPLETIYATVAFGAAHGIPTLLNPAPAVPELDVERLRTL
SFLTPNETELAILSGMPVASETEVEAAARSLIAKGVRTVIVTMGARGALLVEEKGATRIA
PVRVTPKDTTGAGDAFIGSFAHYYTQNGDIAAALRKAVRYAADSITRNGTQSSYATLAEF
EAFCATIDA