Protein Info for Rru_A2275 in Rhodospirillum rubrum S1H

Annotation: Binding-protein-dependent transport systems inner membrane component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 299 transmembrane" amino acids 32 to 53 (22 residues), see Phobius details amino acids 93 to 121 (29 residues), see Phobius details amino acids 134 to 153 (20 residues), see Phobius details amino acids 158 to 178 (21 residues), see Phobius details amino acids 201 to 207 (7 residues), see Phobius details amino acids 214 to 244 (31 residues), see Phobius details amino acids 262 to 282 (21 residues), see Phobius details PF00528: BPD_transp_1" amino acids 111 to 292 (182 residues), 106.8 bits, see alignment E=5.7e-35

Best Hits

Swiss-Prot: 68% identical to NIKC_ECO57: Nickel transport system permease protein NikC (nikC) from Escherichia coli O157:H7

KEGG orthology group: K02034, peptide/nickel transport system permease protein (inferred from 100% identity to rru:Rru_A2275)

MetaCyc: 68% identical to nickel ABC transporter membrane subunit NikC (Escherichia coli K-12 substr. MG1655)
7.2.2.i [EC: 7.2.2.i]; 7.2.2.- [EC: 7.2.2.i]

Predicted SEED Role

"Nickel transport system permease protein NikC (TC 3.A.1.5.3)" in subsystem Transport of Nickel and Cobalt (TC 3.A.1.5.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.i

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RS20 at UniProt or InterPro

Protein Sequence (299 amino acids)

>Rru_A2275 Binding-protein-dependent transport systems inner membrane component (NCBI) (Rhodospirillum rubrum S1H)
MTMPDCQQGHRPPDAAPLRGWLARLPIGRSWSLRLALLVLVALIASAIVGQSLLPGDANA
IDLAARLRPPSWEHWLGTDHLGRDIFLRLLAGAGVSLGSVALCLALVLAMGIAVGGAAGV
LGGRADQAIMRVTDVFLTFPTLVLSLFMVGVLGSGLTNVIIAIALSHWAWYARIVRGIVL
SLRERDFILAARLSGAGRVSIFVEHLLPATASQLLVLASLDIGHMMLHVAGLSFLGLGVA
PPMAEWGVMINDARQFVWTQPMLMVWPGVALFVSVMTFNLLGDALRDRLDPHLCAEHGH