Protein Info for Rru_A2185 in Rhodospirillum rubrum S1H

Annotation: Pyruvate ferredoxin/flavodoxin oxidoreductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1168 transmembrane" amino acids 729 to 750 (22 residues), see Phobius details PF02775: TPP_enzyme_C" amino acids 465 to 549 (85 residues), 24 bits, see alignment 4.4e-09 PF01558: POR" amino acids 737 to 921 (185 residues), 72.3 bits, see alignment E=8.4e-24 PF20169: DUF6537" amino acids 951 to 1150 (200 residues), 228.6 bits, see alignment E=1.1e-71

Best Hits

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSB0 at UniProt or InterPro

Protein Sequence (1168 amino acids)

>Rru_A2185 Pyruvate ferredoxin/flavodoxin oxidoreductase (NCBI) (Rhodospirillum rubrum S1H)
MTIQAPINRSELSPQAFAPELEDKYALTGGRAYMTGTQALVRLALAQRRSDRKAGLDTRG
FISGYRGSPLGGFDKELWKARPWLEAEGIVFKPGINEDLAATAVWGSQQVGLFKGARQQG
VFGIWYGKGPGIDRSGDVFKHANNAGTAPLGGVLLIAGDDHAAKSSTAAHQCEYSFMDAM
IPVLHPAGLEEVISFGLFGLALSRYSGCWVALKTIAETVDSSAPVLLDPDPPAFLLPAEG
QAPVGGLHIRWPDPALDQEARLMRHKLYAALAFARVNRIDKVVMDSPVPRLGIVSVGKAY
LDVRQALDDLGIDPAMAAAIGLRLYKVGMPWPLEREGVRAFAEGLEEILVVEEKRAVVEN
QIKEQLYNWREDVRPRVVGKFDESGAWLLPSAGELTPAMVARALAGRIGRFVTGPSIRDR
LDWLERKDAALAGPTAVLKRLPTYCAGCPHNTSTTLPEGSRALAGIGCHYMVTWMPERAT
ATFSQMGGEGVAWIGQAPFTDEPHVFVNLGDGTYFHSGILAIRAAVAAGVNVTYKILVND
AVAMTGGQPIDGLLSVDGLSRQLEGEGVGKIVVVSDEPGKYPIGTVFAAGVTIRHRDDLD
AIQKDLRGWPGVSAILYDQTCAAEKRRRRKRGLLADPDRRVFINDLVCEGCGDCGKVSNC
VAIEPLETEFGRKRSVDLSACNKDYSCLKGFCPSFVTVSGAEVRRPEGVGEVAFPPLPEP
RLADLGAPYSILVTGIGGTGVVTIGALLGMAAHLEGKGVTVLDQTGLAQKNGAVTTHVRI
AASQEALHAVRIAAGNANLLLGCDALTAAGPEVLAKARPRATDAVINTRPVMTAAFTRDP
DSRYPEAEVRAALSATTRRAFFLDATTIATALMGDSLATNPFMIGYAWQKGLLPLGRAAI
ERAITLNGAAVAFNLEALLWGRRAAHDLEAVTALLDRAGGGPEHHRRSESVAETIERRAT
FLAAYQNAALAARYRRLVEAVVAVEKRVRPGGEALSEAVAKAYFKLLAYKDEYEVARLYS
DGRFAQALAARFSGKPRLTVHLAPPLMSPRDPTTGRLRKRAFGAWIFPLFRLLARLKGLR
GTPFDPFGQTSERRLQRRLITEYETTLGVILERVDPQGYDLAVEIAGLPLEMRGFGPVLV
EAVTKAQARERTLLAAFLAPRPLASAAE