Protein Info for Rru_A2153 in Rhodospirillum rubrum S1H

Annotation: TonB-like (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 276 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13103: TonB_2" amino acids 187 to 267 (81 residues), 37 bits, see alignment E=2.9e-13 PF03544: TonB_C" amino acids 197 to 275 (79 residues), 48.1 bits, see alignment E=1.3e-16 TIGR01352: TonB family C-terminal domain" amino acids 199 to 275 (77 residues), 55.9 bits, see alignment E=2.1e-19

Best Hits

KEGG orthology group: K03832, periplasmic protein TonB (inferred from 100% identity to rru:Rru_A2153)

Predicted SEED Role

"Ferric siderophore transport system, periplasmic binding protein TonB" in subsystem Campylobacter Iron Metabolism or Hemin transport system or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSE2 at UniProt or InterPro

Protein Sequence (276 amino acids)

>Rru_A2153 TonB-like (NCBI) (Rhodospirillum rubrum S1H)
MRGPSGRTWGIAGSAALHLGVVAALMASPTPETPPTPETAPMMTLEFVMAPPPPPPPPPP
PAEVAPPPEIAPPPPFEPVIASTSALAEPLIAPPEEPPPEVKREPEREPPPKPEAKPKPK
PKPKAERAPDPIETPAKKKPEKTTSSDQASSTPSDAPASFDSAPQGVASATPGPTRASAS
GPPPSYLSRLLADLASHKNYPRRSRSRGEQGEARLFLVIGRDGSVLSSKLMRSTGYADLD
AAVNEMVDKANPLPPLPDDYPEARMELIVPITFTLR