Protein Info for Rru_A2136 in Rhodospirillum rubrum S1H

Annotation: hypothetical protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 190 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 69 to 88 (20 residues), see Phobius details amino acids 99 to 119 (21 residues), see Phobius details PF11351: GTA_holin_3TM" amino acids 12 to 122 (111 residues), 87.9 bits, see alignment E=3.9e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2136)

Predicted SEED Role

"Methionine synthase I, cobalamin-binding domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSF9 at UniProt or InterPro

Protein Sequence (190 amino acids)

>Rru_A2136 hypothetical protein (NCBI) (Rhodospirillum rubrum S1H)
MWDRILGLLGAGGLSAVKALVGRFVADKDAAAAAVHAETLRQLEIYGAESAGRSGATAWD
SLVDGLNRLPRPLMAFAVMAMMVWAPLDPIGFAEAMRAYALVPEWLATTLFGVAAFYFTA
RHFEKRLELGGPPKVPLERVIGDIAAMEAMRPKNNRADKNATALASPTGQSPLDNQSLLD
WRRRNGGNIK