Protein Info for Rru_A2060 in Rhodospirillum rubrum S1H

Annotation: FAD linked oxidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 978 PF01565: FAD_binding_4" amino acids 53 to 192 (140 residues), 99.3 bits, see alignment E=3.3e-32 PF02913: FAD-oxidase_C" amino acids 284 to 537 (254 residues), 171.3 bits, see alignment E=6.3e-54 PF13183: Fer4_8" amino acids 571 to 651 (81 residues), 31 bits, see alignment E=6e-11 PF13534: Fer4_17" amino acids 577 to 652 (76 residues), 22.2 bits, see alignment 3.4e-08

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 100% identity to rru:Rru_A2060)

Predicted SEED Role

"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.99.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSN5 at UniProt or InterPro

Protein Sequence (978 amino acids)

>Rru_A2060 FAD linked oxidase (NCBI) (Rhodospirillum rubrum S1H)
MDGGGGGAVPEWAKIGEGLGTALAEAGFRGDVLFDWGSRVAASTDNSIYQIVPEAVVCPR
DRADLRVFLAVLARPAFRDLSVTGRGGATGTNGQGLNGGIVVDFRRYMTRILAADLEAGW
IEVEPGVVLDQVNAALADRGSALFFAPDTSTASRCTIGGMVSTDACGQGSRVYGKTGDNV
LTLDVMLIDGAEARLRRLEGPALEALATSTEPAADALRAALEACDDGAPALKAAVPHLSR
RFVGYDLINARPSPSVFDPVRLIVGSEGTLALVCSARLALTRRPIHKRLAVIAYRDFDGA
LASAQALLAHNPDAIESLDDTVHTLAYQGGLLDGLPERLRTPGPTGKIPVSNYVEFTDDD
PIVLSGRLAALEDALRSEPSVVGWHIAKDPAEIARIWGIRKSAVGLLGGSAGRRRPVAFV
EDCVVPPANLRGFVADFRALLEGEGLTFGMFGHVDVGCIHVRPALDLADAGDQARMKSIS
DAVVAIVRKHGGIFWGEHGKGVRGQYLPEMVGPEAYAAFARVKRAFDPRNRLNPGKLVTP
EGDAAGLYKVDATPLRLPNPADDADPFADAFRCNGNAQCQAYSTSVPMCPSFKATGEKRH
SPKGRADLLRAWHGLVSAGDPVAEDVAEEVYEALDGCLGCKACLSSCPIHVDVPELKSLF
LDRYHQTRKRPLGDRLLAELETLGPLAARLPGLGNVLSRLGGPLTARAAGLVDLPTLSDP
PLAPRLRRMRVPVVAGPSARPAPRGVFVIQDGFTSHFDAGAVEAVVGGLQALGYAPQVVA
LFPTGKALHVKGFRNRFLETAKAARARLDALTPGVPRVGVDPAAVLMLRQEYVQAGLAPR
EPVWLIQEFLAEEAKRGVAWPQAKAGGPPVRVMLHCTERTAVPTAGAQWKQVFAAIGLVA
EVPEAGCCGMSGAFGHEARHRTISATLWALSWRKPVTGASGPVAATGFSCRSQAKREEGT
ALPHPMALLAGALAPPRR