Protein Info for Rru_A2041 in Rhodospirillum rubrum S1H

Annotation: Aminotransferase class-III (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00202: Aminotran_3
  • amino acids 28 to 445 (418 residues), 314.7 bits, E=4.1e-98

Best Hits

Swiss-Prot: 52% identical to GATP1_SOLLC: Gamma aminobutyrate transaminase 1, mitochondrial (GABA-TP1) from Solanum lycopersicum

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A2041)

MetaCyc: 52% identical to gamma aminobutyrate transaminase (Solanum lycopersicum)
RXN-6902 [EC: 2.6.1.96]

Predicted SEED Role

"Omega-amino acid--pyruvate aminotransferase (EC 2.6.1.18)" in subsystem Pyruvate Alanine Serine Interconversions (EC 2.6.1.18)

MetaCyc Pathways

• superpathway of coenzyme A biosynthesis II (plants) (8/10 steps found)
• β-alanine degradation II (2/2 steps found)
• 4-aminobutanoate degradation IV (2/3 steps found)
• β-alanine biosynthesis II (4/6 steps found)

KEGG Metabolic Maps

• Alanine and aspartate metabolism
• Propanoate metabolism
• Valine, leucine and isoleucine degradation
• beta-Alanine metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.18

Use Curated BLAST to search for 2.6.1.18 or 2.6.1.96

Sequence Analysis Tools

See Q2RSQ4 at UniProt or InterPro

Protein Sequence (455 amino acids)

>Rru_A2041 Aminotransferase class-III (NCBI) (Rhodospirillum rubrum S1H)
MVSNALRDADLSYTIHPYTNLVAHETKGPLIAVRGEGVRVFDDKGKDYIEGMAGLWCASL
GFSEPRLAAAAARQMAELPFFHMFSHKSHEPGIRLSEELVKRAPVPMARAFFCNSGSEAN
DTAIKMIWYINNALGRPQKKKIIARKRAYHGVTVASASLTGLPANHRDFDLPIANILHTS
SPDYYREGKPGESEEAFAKRCADELEAMILAEDPNTVAAFFAEPIMGAGGVVLPPKGYFE
HIQAVLKKYDILLVADEVICGFGRTGQYWGSQTFGLKPDILTCAKALSSAYMPISAVLVT
EEVYKPLRDNSGKIGTFGHGYTYSAHPVAAAVALETLAIYDERDILGNVAVSGARLQERL
RSFADHPLVGNVRGIGLIGAIELVADKATHGAFPASDAVGPRVVTKAEEAGVILRAMAGD
VVAFSPPLIITPEEVDQMMDRFTVALEAVTAEVLG