Protein Info for Rru_A1970 in Rhodospirillum rubrum S1H

Annotation: PTS fructose IIC component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 575 transmembrane" amino acids 247 to 271 (25 residues), see Phobius details amino acids 289 to 310 (22 residues), see Phobius details amino acids 321 to 347 (27 residues), see Phobius details amino acids 367 to 395 (29 residues), see Phobius details amino acids 407 to 426 (20 residues), see Phobius details amino acids 446 to 468 (23 residues), see Phobius details amino acids 480 to 500 (21 residues), see Phobius details amino acids 506 to 526 (21 residues), see Phobius details amino acids 547 to 567 (21 residues), see Phobius details PF02302: PTS_IIB" amino acids 7 to 94 (88 residues), 23.6 bits, see alignment E=6.6e-09 amino acids 118 to 207 (90 residues), 70.4 bits, see alignment E=1.7e-23 TIGR00829: PTS system, Fru family, IIB component" amino acids 117 to 199 (83 residues), 109.9 bits, see alignment E=6.1e-36 TIGR01427: PTS system, Fru family, IIC component" amino acids 228 to 569 (342 residues), 464.6 bits, see alignment E=2.4e-143 PF02378: PTS_EIIC" amino acids 246 to 513 (268 residues), 70.8 bits, see alignment E=1.1e-23

Best Hits

Swiss-Prot: 71% identical to PTFBC_XANCP: PTS system fructose-specific EIIB'BC component (fruA) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K02769, PTS system, fructose-specific IIB component [EC: 2.7.1.69] K02770, PTS system, fructose-specific IIC component (inferred from 100% identity to rru:Rru_A1970)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RSX5 at UniProt or InterPro

Protein Sequence (575 amino acids)

>Rru_A1970 PTS fructose IIC component (NCBI) (Rhodospirillum rubrum S1H)
MSQFIAVVGGGERSTQALLVAEALRRAASGAGHRIDIEVRSDQGVVNALSDDAIVRARAV
ILIGTGDLDVGRFPGLPKLETTIEAVLADVGAVLGRAEGAELAGSVAATDDGVRRIVAIT
SCPTGIAHTFMAAEGITQAAKALGYQARVETQGSVGSRDTLSDDEIAQADIVLIAADTQI
DLARFDGKRVFLSGTKPAIADGKALIARALAEATLQGGKKSLVDTVEAGKAQRSAQRTGA
YKHLMTGVSFMLPFVVAGGLLIALAFALGGINAFDEANKGTLAYDLFQIGAKSAFVLMVP
ALAGYIAFSIADRPGIAPGMIGGLVAANLGAGFLGGIIAGFIAGYVTAWFNRTIRLHRNL
EGLKPVLILPVLGTVVTGLLMIYVVGTPVAGLLSWLTEALRGMQGSSAIVLGLLIGAMMA
FDMGGPVNKAAYAFSTGLLASEVYTPMAAAMVAGMTPALGVALASRLFRSRFTASEREAG
GAAAVLGLAFITEGAIPFAASDPFRVIPALMAGSAAAGAISMTVGAELKVPHGGIFVLPI
PNAVTHLLGYIVALVVGTLITALVLRITKRPVAVL