Protein Info for Rru_A1931 in Rhodospirillum rubrum S1H

Annotation: Ferredoxin--nitrite reductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 PF03460: NIR_SIR_ferr" amino acids 52 to 111 (60 residues), 73.5 bits, see alignment 9.6e-25 amino acids 350 to 401 (52 residues), 54.2 bits, see alignment 9.8e-19 PF01077: NIR_SIR" amino acids 119 to 272 (154 residues), 166.4 bits, see alignment E=3.6e-53 amino acids 456 to 550 (95 residues), 34.7 bits, see alignment E=1.2e-12

Best Hits

KEGG orthology group: K00366, ferredoxin-nitrite reductase [EC: 1.7.7.1] (inferred from 100% identity to rru:Rru_A1931)

MetaCyc: 45% identical to assimilatory sulfite reductase (ferredoxin) (Allochromatium vinosum)
Sulfite reductase (ferredoxin). [EC: 1.8.7.1]

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.7.1 or 1.8.1.2 or 1.8.7.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RT14 at UniProt or InterPro

Protein Sequence (556 amino acids)

>Rru_A1931 Ferredoxin--nitrite reductase (NCBI) (Rhodospirillum rubrum S1H)
MYRYDEFDAAIVADRISEFRDQVNRRLSGELDEEAFRPLRLMNGVYLQLHAYMLRVCIPY
GEINATQLRRLGAIAQRYDRGYGHFTTRQNIQFNWVALSDIPAVLEELAEVGMHAIQTSG
NCIRNTTTDPLAGVAADEVEDPRPWAELIRQWSTFHPEFTFLPRKFKVAITGASHDRAAI
RFHDIGLELAPIGGGEIGFKVFVGGGMGRTPRLGRLLRDDLPKQHLLSYIEAILRVYNRQ
GQRENKYKARIKILVDSLGVEAFRAEVDAEWEAMGRATIDVPEAEIARIQSYFVPQDSAP
EDGGLAASRAITKRRASDPAFAGWLDANVHAHKVAGHAGVTISLKPAGGIPGDATTAQLE
TIADLAERYSKGLLRVTHEQNLLLPHVRQEDLPALWAALVAAGLETANVGRIGDIISCPG
LDYCSLATARSIPIAQALSARFADPARLRDIGPITLNISGCINACGHHHAGNIGILGLEK
TGNEAYQLVLGGAADETAAIARITGQGFSADAIVGAVETVVDTYIGLRQDGETFIETFRR
VGVTPFKEALYGSVAA