Protein Info for Rru_A1883 in Rhodospirillum rubrum S1H

Annotation: Magnesium and cobalt transport protein CorA (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 331 transmembrane" amino acids 270 to 293 (24 residues), see Phobius details amino acids 305 to 325 (21 residues), see Phobius details TIGR00383: magnesium and cobalt transport protein CorA" amino acids 27 to 331 (305 residues), 216.4 bits, see alignment E=3.2e-68 PF01544: CorA" amino acids 30 to 327 (298 residues), 174.5 bits, see alignment E=1.7e-55

Best Hits

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 100% identity to rru:Rru_A1883)

Predicted SEED Role

"Magnesium and cobalt transport protein CorA" in subsystem Campylobacter Iron Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RT62 at UniProt or InterPro

Protein Sequence (331 amino acids)

>Rru_A1883 Magnesium and cobalt transport protein CorA (NCBI) (Rhodospirillum rubrum S1H)
MVKGLPMILGYAEENGRLRRLPVPLDETERVIWYDLFCPTPREAAQVASVLGIEIPTREE
MEEIEISSRLYQEDDAIFMTATLLSRTDTDQPQSSPVTFILAGARLVTIRYEEPRAFQAF
PTRAEKAGLGCFSGEKTLLALLEAVVDRLADVLERDAREIDRLSQSIFSHDSSGSRDSRD
KDFQKILKLIGRKGDLTSDIRESMVSLQRVFVYLTQIATERKTGKDSRTRLRTLHRDAQS
LTDHATFLSSKITFLLDATLGMINIEQNAIIKLFSVVAVIFLPPTLVASIYGMNFRYMPE
LEWPFGYPLAIALMLASAIIPYRLFKRWGWL