Protein Info for Rru_A1846 in Rhodospirillum rubrum S1H

Annotation: Twin-arginine translocation pathway signal (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 364 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF03480: DctP" amino acids 49 to 321 (273 residues), 161.6 bits, see alignment E=1.3e-51

Best Hits

Swiss-Prot: 36% identical to TAKP_RHOS4: Alpha-keto acid-binding periplasmic protein TakP (takP) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A1846)

Predicted SEED Role

"TRAP transporter solute receptor, unknown substrate 6"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RT99 at UniProt or InterPro

Protein Sequence (364 amino acids)

>Rru_A1846 Twin-arginine translocation pathway signal (NCBI) (Rhodospirillum rubrum S1H)
MDRREFLSASAAAATGGLSLDGLSRPALANGAKTLTMVTTWPKDYVGLGESASRLAARVR
TMSGGRLSITVYAAGELVPAFEAFEAVANGTADLYHGAETYWESRSSAFNFFCAVPFGLT
AIETSAWIHHGGAQALWDALSAPYGIKPMLASATGVQMGGWFNKEIKRVEDFKGLRMRIP
GLGARILKEVGAVPVALPGSQIHDALRDGAIDAAEWIGPWSDLALDLQKVARYYYYPGFH
EPGTSLAVGINLGVWRGLSDQERAIIEAACGAEHAFSLAEYNARNGDALHTLVTNHGVQL
RAFPTQVLLELGKTAGRVVRAAAADSPETRRIYDHYTAFRRKALTWAQLSDQAFWNARSL
PFEY