Protein Info for Rru_A1840 in Rhodospirillum rubrum S1H

Annotation: Penicillin amidase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 821 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF01804: Penicil_amidase" amino acids 70 to 803 (734 residues), 649.5 bits, see alignment E=5.1e-199

Best Hits

KEGG orthology group: K01434, penicillin amidase [EC: 3.5.1.11] (inferred from 100% identity to rru:Rru_A1840)

Predicted SEED Role

"Penicillin acylase II (EC 3.5.1.11)" (EC 3.5.1.11)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTA5 at UniProt or InterPro

Protein Sequence (821 amino acids)

>Rru_A1840 Penicillin amidase (NCBI) (Rhodospirillum rubrum S1H)
MTRLGHWMLRLGLGAVALGLVAALVLGLALTGSLPRTSGRIEVTTGGALPVDDPQRPGSS
TTWGGLSGPIDIIRDRYAIPTIRAANDRDAAFALGVVHAQDRLWQMEGMRRLGAGRMAEL
LGPRALPIDRFMRTLGLHALAAETYRRMPADERAVMEAYCAGVNQIIGAKWTIPPPEFLM
LLARPEPWRPVDSLVWGRLMGLWLSADWQEELVRAALAKSLSPERLKSLWPAFGRSDVAA
RPAAAPLSGEAALALLAAFPKALAPTLASNAWAVGGGKTASGQPLLASDPHLGFQAPIQW
YLARLETPERTLTGATFPGVPLTVIGTNERVAWGLTTTHSDTMDLFVERVVDADHYLTEN
GPEPWLRRTETLAVRGAPSETLEVRASRHGPVISDVLPAASADLGHAALGEGEALTLAAT
ALRPDDQTALALRALNRAGTADEVRKAARGFQSPQQNLIYATAEGAIGRLSPGLTPLRAG
GPGLLPQTGWTSTSRWTGYIPFEDLPAESDPASGFVYNTNSAIVGEDYPHYLIDAWPGED
RAARLARLLAYRDDHGPRDMALYQLDTVSHALETLLPRLLDFPAALRPAGSAVARAHALL
ADPGWSFDMGAHRTEPLIATAWLVAVNRLLFAPAMGPAFAAWERLDPAVLHRALDGAGSW
CDPAADAEGLTGCDRLKARALDEALSGLVESLGGADPFTVTWGEVHRAHFRHPLFRYLPA
LAKLTTLETATGGDDFTLSRGSWGGDRTDPFAHVHGAGLRAVIDFATIAAPGFILATGQS
GHPLSPHYRDMVDLWRRGALITVDGADPSGGHLILEPVGDR