Protein Info for Rru_A1752 in Rhodospirillum rubrum S1H

Annotation: Excinuclease ABC, A subunit (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 TIGR00630: excinuclease ABC subunit A" amino acids 6 to 927 (922 residues), 1464.9 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 132 to 237 (106 residues), 131.8 bits, see alignment E=3.2e-42 PF17755: UvrA_DNA-bind" amino acids 290 to 400 (111 residues), 131.6 bits, see alignment E=5.2e-42 PF00005: ABC_tran" amino acids 807 to 863 (57 residues), 26.6 bits, see alignment 3e-09

Best Hits

Swiss-Prot: 64% identical to UVRA_BACHD: UvrABC system protein A (uvrA) from Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 73% identity to azc:AZC_2887)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTJ3 at UniProt or InterPro

Protein Sequence (950 amino acids)

>Rru_A1752 Excinuclease ABC, A subunit (NCBI) (Rhodospirillum rubrum S1H)
MSTQEIRVRGAREHNLRNVDVTLPRDKLVVITGLSGSGKSSLAFDTIYAEGQRRYVESLS
AYARQFLEMMQKSDVDSIEGLSPAISIEQKTTSRNPRSTVGTVTEIHDYMRLLWARIGVP
HSPATGLPIESQTVSQMVDRTLALPEGTRLYLLAPVARGRKGEFKKELAELQKKGFSRVK
VDGTIYEIPEVPALNKKIKHDIEVVVDRLVVRADIASRLADSFETALELSDGLVFAEDAV
SGERHTFSARFACPVSGFTIDEIEPRLFSFNNPFGACPTCDGLGVTLYFDPELVVPDPSR
TLNRGAVAPWSGQTPPSPYYAQALASIAAHFGADMDTPWKDLPEEMRRIILEGSGKEIIP
LSFDDGTRSYRTQKPFEGVIPNIARRWRETESNWIRDELSRYQGSAPCPACGGYRLKPQA
LAVKINGRHIGEASEVSIAEARAWFAGLEAKLSPKHREIADRILREINERLGFLGNVGLD
YLSLSRNSGTLSGGESQRIRLASQIGSGLTGVLYVLDEPSIGLHQRDNDRLLITLKRLRD
IGNTVIVVEHDEDAIRNADYLVDMGPGAGVHGGTIVAQGTPEQVMANPASLTGQYLTGKR
SVPVPTVRRQGNGKVLTLRGARANNLQNVDVSIPLGTFTCITGVSGGGKSTLVLETLYKA
LARQLHGARDLPGEHDAIEGAEQIDKIVDIDQSPIGRTPRSNPATYTGAFTPIRDWFSGL
PEAKARGYKPGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVTCDVCKGKRYNRETLDV
TFKGKSIADVLDMTIEEAGDFFKAVPAVRDKMEMLQQVGLDYIRLGQQATTLSGGEAQRV
KLAKELSRRATGRTLYILDEPTTGLHFEDVRKLMEVLQALVDTGNTVVVIEHNLEVIKTA
DHIIDMGPEGGSGGGRVVAQGTPEEVAANPASHTGSYLKPYLSALARRSA