Protein Info for Rru_A1726 in Rhodospirillum rubrum S1H

Annotation: Transcription-repair coupling factor (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1177 PF17757: UvrB_inter" amino acids 135 to 219 (85 residues), 76.5 bits, see alignment 5e-25 TIGR00580: transcription-repair coupling factor" amino acids 149 to 1102 (954 residues), 1012.4 bits, see alignment E=0 PF21132: MFD_D3" amino acids 410 to 477 (68 residues), 26.3 bits, see alignment 2.1e-09 PF02559: CarD_TRCF_RID" amino acids 503 to 558 (56 residues), 70.7 bits, see alignment 3.1e-23 PF04851: ResIII" amino acids 628 to 783 (156 residues), 33 bits, see alignment E=2e-11 PF00270: DEAD" amino acids 628 to 789 (162 residues), 79.3 bits, see alignment E=1e-25 PF00271: Helicase_C" amino acids 828 to 931 (104 residues), 71.1 bits, see alignment E=3.3e-23 PF03461: TRCF" amino acids 1031 to 1118 (88 residues), 94.1 bits, see alignment 1.9e-30

Best Hits

Predicted SEED Role

"Transcription-repair coupling factor" in subsystem DNA-replication or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTL9 at UniProt or InterPro

Protein Sequence (1177 amino acids)

>Rru_A1726 Transcription-repair coupling factor (NCBI) (Rhodospirillum rubrum S1H)
MKNLLESLAVGRRIEAAGLPEGFDALVLGELAARPGVPAVLHVARDDVRLARLAETIAFF
HPAVEILEFPAWDCVPYDRVSPNVEIVARRLETLSRLSEEPTRQPGGRLVLTTASAILQR
VPPRQILERGVFSARVGGRLDLGKLLDHLARHGYGRSEQVMEPGEYAVRGGIVDIFPPGA
PEPLRLDLFGDELDSLRSFDPVSQRTTGQRDALILRPMSEVVLDKESISRFRSGYRELFG
TPSAADALYEAISAGLPFMGMEHWLPLFHEGMDTLFAYVPDGPVTLDPGLDGALRSRQDQ
IFEYFEARRLMESVGDGAKASEKPGGGMIYHALPPPRMFLEEDEFLRHCAGRPGAAFSAY
AAPDVATEKGVVGDFLGRPGHEFADIRARAGGNVFDALRDHAQALRAAGKRVVLTAATMG
ARERMTGVLREHGLSPIVTAETWAEALERAKKATVVLTLILDRGFETPDLAVISEADVLG
DRLSRPVRKKKLGDKFIPDISALSEGDLVVHVDHGIGQYEGLETLTAGGAPHDCLRVVYA
DNNRLYVPVENIEVLSRYGSEQAGVQLDKLGGVAWQARKAKLKQRIRDMAEQLIGVAAAR
QLKVGEVISPPEGLYDEFAARFPYAETDDQLRAIADTLDDLAAGRPMDRLICGDVGFGKT
EVALRAAFATAMSGRQVAVVVPTTLLARQHHLTFKERFAGLPVRIGQLSRLVTARDTKAV
KEEMAAGTLDIVVGTHALLAKTVRFRDLGLLIVDEEQHFGVAHKERLKQMRADVHVLTLT
ATPIPRTLQLALTGVREMSIIATPPVDRLAVRTFVLPFDPVVVREAILRERFRGGQCFYV
CPRLTDIDKVMERLTTLVPDIRAVVAHGQMAPSRLEEVMTAFADGQYDVLVATNIVESGL
DIPRANTIIIHRADMFGLAQLYQLRGRVGRARARGYAYLTLPPGRTVSKTAAKRLDVMQT
LDTLGAGFTLASHDLDIRGAGNLLGDEQSGHIKEVGIELYQQLLEEAVAAAREGPGVEEA
SGAWSPQIQLGTPILIPDSYVKDLGLRLGLYRRIAGVTDEAEIDEMAAEMVDRFGPLPDE
VENLLKVVTIKVLCRRANAEKVDAGPKGAVLSFRDNLFPNPGGLVRFIGQNVATVKLRPD
HKLVYRRDWEVARERIQGLGKLMRTLADIADEERPGR