Protein Info for Rru_A1706 in Rhodospirillum rubrum S1H

Annotation: Lytic murein transglycosylase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details TIGR02283: lytic murein transglycosylase" amino acids 77 to 375 (299 residues), 364.3 bits, see alignment E=2.4e-113 PF13406: SLT_2" amino acids 78 to 372 (295 residues), 363.7 bits, see alignment E=1e-112 PF08823: PG_binding_2" amino acids 382 to 430 (49 residues), 23.6 bits, see alignment 7.5e-09 PF01471: PG_binding_1" amino acids 393 to 446 (54 residues), 51.2 bits, see alignment 1.7e-17

Best Hits

KEGG orthology group: K08305, membrane-bound lytic murein transglycosylase B [EC: 3.2.1.-] (inferred from 100% identity to rru:Rru_A1706)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-)" in subsystem Peptidoglycan Biosynthesis (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTN9 at UniProt or InterPro

Protein Sequence (454 amino acids)

>Rru_A1706 Lytic murein transglycosylase (NCBI) (Rhodospirillum rubrum S1H)
MARLGSPYKKQKSVPMARRPFALAALPVVLLALSSCAGADQSQRSGGTGGGRSAPGMAPV
SPIAPAAALSPAAEQAAFAQWLVGMRAEALAAGISRATVDSALGRARIEPRIVELDRKQP
EFNKTLAGYFASTLPDSRIAKAREMMALHAPLLRSLEQRYGVPGRFLVAFWGLETNFGGT
LGSFRVVDALSTLAFEGRRGAFFRAQLLDALRIIDAGHVSADAMIGSWAGAMGQTQFMPS
TFRAHAVDYDGDGRIDIWGSLPDALASAAKYLSDLGWKGAEPWGWEVVLPAGLDLARVGL
EERRPLADWAALGLRGADGRALGAGARAGVTAALLLPAGYRGPAFLVTDNYFSILKWNRS
MLYALAVGLLADRAAGGGPLVHPPPADEAPLRSADVAEIQSRLSALGYDAGTADGVIGAQ
TRVAIRAYQASIGAPADGYANDALLADLRRRSGR