Protein Info for Rru_A1642 in Rhodospirillum rubrum S1H

Annotation: putative sulfonate/nitrate transport system substrate-binding protein (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF09084: NMT1" amino acids 56 to 268 (213 residues), 254.7 bits, see alignment E=9e-80

Best Hits

Swiss-Prot: 53% identical to Y357_HAEIN: Putative thiamine biosynthesis protein HI_0357 (HI_0357) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 100% identity to rru:Rru_A1642)

Predicted SEED Role

"Hydroxymethylpyrimidine ABC transporter, substrate-binding component" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTV3 at UniProt or InterPro

Protein Sequence (335 amino acids)

>Rru_A1642 putative sulfonate/nitrate transport system substrate-binding protein (NCBI) (Rhodospirillum rubrum S1H)
MPCLRQAAFPSRVSRGLVIALVCALVHTLAGPIAAARAEDKPAPAKVSVLLDWFINPDHG
PLIVAQDLGYFKDAGLEVDLVAPADPNDPPKLVAAGKADIAVGYQPQLVMQVAEGLPLMR
FGTLVATPLNCLVVLKDGPIKSVADLKGRKVGFSVGGFEDALLGAMLDNAGVKADEVTLV
NVNFSLSPAVISGQVDAVIGPFRNFELNQMDLAGHPGTAFYPEEHGVPLYDELVFVTNIA
LKGDPRLVAFLDAVERGTHYIVNHPEEAWTLFKAHSPDLDDELNHRAWIDTVARFSMTPG
ALDERRYARFAGFLQSRGLIKTVPPLASYAIEPGL