Protein Info for Rru_A1608 in Rhodospirillum rubrum S1H

Annotation: MscS Mechanosensitive ion channel (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 868 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 220 to 242 (23 residues), see Phobius details amino acids 262 to 286 (25 residues), see Phobius details amino acids 299 to 321 (23 residues), see Phobius details amino acids 342 to 359 (18 residues), see Phobius details amino acids 371 to 391 (21 residues), see Phobius details amino acids 435 to 457 (23 residues), see Phobius details amino acids 463 to 484 (22 residues), see Phobius details amino acids 517 to 539 (23 residues), see Phobius details amino acids 560 to 584 (25 residues), see Phobius details amino acids 606 to 628 (23 residues), see Phobius details amino acids 634 to 656 (23 residues), see Phobius details PF00924: MS_channel_2nd" amino acids 651 to 717 (67 residues), 79.8 bits, see alignment 1.3e-26 PF21082: MS_channel_3rd" amino acids 726 to 807 (82 residues), 50.1 bits, see alignment E=3.2e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A1608)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RTY7 at UniProt or InterPro

Protein Sequence (868 amino acids)

>Rru_A1608 MscS Mechanosensitive ion channel (NCBI) (Rhodospirillum rubrum S1H)
MRCVWAAVAAVFCLVAVALPVSAQTSPGPAATTAAAAPEVPVLDRLKKAAATWEPTLNDV
DKRLNRPLSGRDAETLDALASRLRAVRDEAVLFRQAATDRLAETEKLIEALGPPPKDGEG
EEAKDMKARRQSYTDLLGTWKSRQADIEVSAARAETLLNRISEIRRRTLVTSLFDPTPLP
WMPDVLAQGGPELIDGLVAIAASPVNWYQSGDEADRRKAAFNAIGVWIILAGGTGWVVRW
WVQRRFGRRPDIENPPYGRRLIAALAEATAEGIIPALVLGGMIAWITKTWTDDQGLFTRV
MLGGLFNVLLVLITRAVTRAALSPGLPSWRLTDHGDQQASKLAHIVVVLAMVVAVDRFMT
GLAGDMPPSDASTWIVSALFKLFEGLILIRLSNADLWARPKPEDGAEDGAPKVQPLATPS
QEDDEAKAGEGAFRLLLLLVRLAVMLVTVVGMMAGLVGYGRLGIFLIDGLLATCAILGAA
LVLRGLLHELIGVAVTWSWLRDRAGYEGPSLNKMKFWLQALFDPLLIVGVVMVASPSWGV
PWRDVLDGTVTLLTGVTIGSVRISIVDIAVGILVFLVAMAITRVAQGTLQRKVLSQTGMD
AGVRHSLTAVLGYIGLVAAAALAVGTMGIDLTNIALIAGALSVGIGFGLQNIVNNFVSGL
IILVERPVKVGDWVIIGSHEGLVKRISFRATELETFTQASVVIPNAEILSSPFTNLTLRN
RLGRIDVSVLVIMNSDTRKVRDLLLEIARAHPQVLTLPAPWVVLKAFADTGLEFEVRSYT
SNVMNRGTIASDMRLEIDRRFREEGVIMPAPLRPIITPGTGSVEQTAADHDLPAGARPVE
EKPVAESKPVEVKKPAAGGRPATTGDSR