Protein Info for Rru_A1591 in Rhodospirillum rubrum S1H

Annotation: Phosphatidate cytidylyltransferase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 268 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 28 to 44 (17 residues), see Phobius details amino acids 50 to 69 (20 residues), see Phobius details amino acids 75 to 92 (18 residues), see Phobius details amino acids 104 to 127 (24 residues), see Phobius details amino acids 133 to 151 (19 residues), see Phobius details amino acids 172 to 191 (20 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details PF01148: CTP_transf_1" amino acids 3 to 258 (256 residues), 176 bits, see alignment E=6.8e-56

Best Hits

KEGG orthology group: K00981, phosphatidate cytidylyltransferase [EC: 2.7.7.41] (inferred from 100% identity to rru:Rru_A1591)

Predicted SEED Role

"Phosphatidate cytidylyltransferase (EC 2.7.7.41)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 2.7.7.41)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.41

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RU04 at UniProt or InterPro

Protein Sequence (268 amino acids)

>Rru_A1591 Phosphatidate cytidylyltransferase (NCBI) (Rhodospirillum rubrum S1H)
MLKTRILSALVLAPPVLAAAFFGSPWFDALAALAGALMAWEWIRLCRGGFGLTGWTMAAL
MALTGALATRFPLDVLLGLALATPMIRLAMAGEDRLRGGMEEEGPWWITAGVPYLGLPLV
ALVWIRGEGGWETLFWLLAVVWATDIGAYACGRTLGGPLLAPRISPKKTWSGLLGGMGSA
ALAGWGLALAFGYAPPLWVILFAPGLAVIAQAGDLFESSMKRRFNVKDSSNLIPGHGGLL
DRVDGLLAAAPPVACVVALQGGGIGLWQ