Protein Info for Rru_A1548 in Rhodospirillum rubrum S1H

Annotation: Malonyl-CoA decarboxylase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 PF17408: MCD_N" amino acids 93 to 183 (91 residues), 75.9 bits, see alignment E=2.2e-25 PF05292: MCD" amino acids 186 to 449 (264 residues), 342.8 bits, see alignment E=1.4e-106

Best Hits

KEGG orthology group: K01578, malonyl-CoA decarboxylase [EC: 4.1.1.9] (inferred from 100% identity to rru:Rru_A1548)

Predicted SEED Role

"Malonyl-CoA decarboxylase (EC 4.1.1.9)" (EC 4.1.1.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RU47 at UniProt or InterPro

Protein Sequence (478 amino acids)

>Rru_A1548 Malonyl-CoA decarboxylase (NCBI) (Rhodospirillum rubrum S1H)
MTDPLSANPGFFLRLSALWRDIAGGRGTGAMPPLSPGLDDDDMGVVRQQLNACLEGKGGV
VSAHARAASLGRAYLSLNEEGRIRFLGILAREFSTDHQAVIAAARALIEASSGGDTGAIL
AAETELGRTLTAPRRILLTQFNALPEGVKFLVDLRGELLTHIKTHPELRPLERDLRDLLT
AWFDVGFLDLERITWESSASFLEKIITYEAVHAIQSWDDLKNRLDHDRRLYAFVHPRMPH
EPLIFVEVALVNGISGTIGDLLDLEAPLLDPAQADTAIFYSISNAQSGLAGISFGNFLIK
RVVETLRREFPGLKTFSTLSPIPGFRRWLDGVFAEGDIGPMSSAERKALRAVDDRGAKGA
LKRLIETDGWLTEEGGEEAVKGPLMRLRARYLAVERRLGSGEGVERAYDPVAHFHLTNGA
RVERINWRGDLSANGLRQSMGMMVNYLYKLDEIEKNHEAYQGNAVAAVSGTVKTLLKA