Protein Info for Rru_A1508 in Rhodospirillum rubrum S1H

Annotation: FAD dependent oxidoreductase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00890: FAD_binding_2
  • amino acids 27 to 67 (41 residues), 21.1 bits, 2.4e-08
• PF01266: DAO
  • amino acids 27 to 390 (364 residues), 182.5 bits, E=2.6e-57
• PF16901: DAO_C
  • amino acids 412 to 533 (122 residues), 105.2 bits, E=3.3e-34

Best Hits

KEGG orthology group: K00111, glycerol-3-phosphate dehydrogenase [EC: 1.1.5.3] (inferred from 100% identity to rru:Rru_A1508)

Predicted SEED Role

"Aerobic glycerol-3-phosphate dehydrogenase (EC 1.1.5.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization or Glycerolipid and Glycerophospholipid Metabolism in Bacteria or Respiratory dehydrogenases 1 (EC 1.1.5.3)

MetaCyc Pathways

• glycerol-3-phosphate shuttle (2/2 steps found)
• glycerophosphodiester degradation (2/2 steps found)
• glycerol and glycerophosphodiester degradation (3/4 steps found)
• glycerol degradation I (2/3 steps found)
• glycerol 3-phosphate to cytochrome aa₃ oxidase electron transfer (1/2 steps found)
• glycerol-3-phosphate to cytochrome bo oxidase electron transfer (1/2 steps found)
• glycerol-3-phosphate to fumarate electron transfer (1/2 steps found)
• glycerol-3-phosphate to hydrogen peroxide electron transport (1/2 steps found)
• nitrate reduction IX (dissimilatory) (1/2 steps found)
• sn-glycerol 3-phosphate anaerobic respiration (1/3 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.5.3

Sequence Analysis Tools

See Q2RU86 at UniProt or InterPro

Protein Sequence (548 amino acids)

>Rru_A1508 FAD dependent oxidoreductase (NCBI) (Rhodospirillum rubrum S1H)
MPRCDPRDGDTPRHDALAALQSGEVFDLLVIGGGATGCGIALDAAGRGLRTALVERFDFA
EGTSGRSTKLVHGGVRYLEAAVRHLDSAQYHLVRDALRERWAFLANAPHLCDRLSLITPL
YSWAEVPYVYAGLTLYDLLSGKRSLGRSRLIGRAEALARCPMLKAEGLKAAVLYYDGQFV
DTRMTIALAMTARRDGAVVANHVALEALIHDDAGTVVGARLRDGLDGASWPIAAKVVINA
TGPFADHLRKMDDPGAKPILRASSGVHIVLEGRFAPPDGGVLIPKTDDGRVLFILPWQGH
ALVGTTEGESEVVDHPPAKAVDVAYLLGHLRRSLALDVSEGDVLSVWAGVRPLVFDPEAI
GTAQLARDHVIIEDPSGLITITGGKWTTYRKMAEQAVDRAVARGGLAPARPCATVSRKVI
GGEAFKKDGAAALVGRFALAGDIARHLHRAYGDRAPLVAELAARGAGARLHPDHPHIEAE
VVYAATLEAAEHGADVLVRRLTLALVDRAAARAAAPRVIALLGDLRGWDAARRAAETALL
DERLSGSL