Protein Info for Rru_A1449 in Rhodospirillum rubrum S1H

Annotation: Bile acid:sodium symporter (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 transmembrane" amino acids 24 to 43 (20 residues), see Phobius details amino acids 58 to 81 (24 residues), see Phobius details amino acids 96 to 119 (24 residues), see Phobius details amino acids 131 to 153 (23 residues), see Phobius details amino acids 166 to 189 (24 residues), see Phobius details amino acids 195 to 214 (20 residues), see Phobius details amino acids 233 to 251 (19 residues), see Phobius details amino acids 257 to 277 (21 residues), see Phobius details amino acids 290 to 318 (29 residues), see Phobius details amino acids 324 to 346 (23 residues), see Phobius details TIGR00832: arsenical-resistance protein" amino acids 18 to 345 (328 residues), 375.6 bits, see alignment E=1.2e-116 PF13593: SBF_like" amino acids 31 to 333 (303 residues), 25.4 bits, see alignment E=8.4e-10 PF01758: SBF" amino acids 64 to 258 (195 residues), 108.1 bits, see alignment E=4.6e-35

Best Hits

Swiss-Prot: 51% identical to ACR3_ALKMQ: Arsenical-resistance protein Acr3 (acr3) from Alkaliphilus metalliredigens (strain QYMF)

KEGG orthology group: K03325, arsenite transporter, ACR3 family (inferred from 100% identity to rru:Rru_A1449)

Predicted SEED Role

"Arsenical-resistance protein ACR3" in subsystem Arsenic resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUE5 at UniProt or InterPro

Protein Sequence (358 amino acids)

>Rru_A1449 Bile acid:sodium symporter (NCBI) (Rhodospirillum rubrum S1H)
MMSVHSDPPAAKVSGKPMGFFERTLTLWVGLCIVVGVTLGHVAPGPFQAIAGLEIAQVNL
PVALLIWLMIIPMLLKIDFAALGTVGRHWKGMGVTLFINWGVKPFSMALLGWLFISTLFR
PWLPADQIDSYIAGLILLAAAPCTAMVFVWSNLTGGEPNFTLSQVALNDLIMVFAFAPIV
GLLLGLSSITIPWDTLLISVALYIVVPVIIAQIWRRALVARGPQAVERVLKTLHPLSLGA
LLATLVLLFGFQGEQILAQPLIIALLAVPITIQVYFNSGLAYLLSKKLGVAHCVAGPAAL
IGASNFFELAVAAAISLFGFQSGAALATVVGVLIEVPVMLSVVKIVNASKGWYEGKPA