Protein Info for Rru_A1386 in Rhodospirillum rubrum S1H

Annotation: DEAD/DEAH box helicase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 677 PF00270: DEAD" amino acids 23 to 192 (170 residues), 148.6 bits, see alignment E=2.1e-47 PF00271: Helicase_C" amino acids 233 to 338 (106 residues), 89.6 bits, see alignment E=2.4e-29 PF03880: DbpA" amino acids 482 to 542 (61 residues), 49.5 bits, see alignment 5.5e-17

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to rru:Rru_A1386)

Predicted SEED Role

"ATP-dependent RNA helicase"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUK8 at UniProt or InterPro

Protein Sequence (677 amino acids)

>Rru_A1386 DEAD/DEAH box helicase (NCBI) (Rhodospirillum rubrum S1H)
MDFFPAGHPLTQALIERNYTEPTAVQTAVLEPGAQGRDLLVSAQTGSGKTVAYGLAIAST
LLGDEAVLEPATEPLALIVAPTRELALQVHRELAWLYGHAGAKVVSCVGGMDPRAETRRL
GEGCHIVVGTPGRLRDHLERGNLAVGRLKAVVLDEADEMLDLGFREDLEFLLEATPQERR
TLLFSATLPKAIVTLAKRYQREAWRIAVAAGKQGHADIEYRAISVAPNEVEHAVVNLLRY
VESPATLVFCNTRESVRHLQAILLERGFAAVALSGELGQGERNQALQALRDGRARVCVAT
DVAARGIDLPNIGLVIHAELPQNAQTLQHRSGRTGRAGRKGISVLLVLFSRKRRAEQLLE
TAGVRAQWGGAPSADDIRALDQERLLQSPLVSEDLTEDDLAMAKALLAVRSPEEIAAALV
RMYRAQLPAAEDVFAAGTAEPSPEPRARRPASRDRDRDGEREPMTEPRPGRNSGLSGPSV
CFRLNVGRQKNADPRWLVPMICRLGKITKQEIGAISIFERDTKIEIAAAFAERFIAAVGQ
VERGDIRIDPWVETSRSKPVDALEVATAGDEAAAAAPRASAPRAPRASEPRVTKPYEPRA
PRSTEPRAPRAARSADRPTEARAPRTAEPRPPRASDRASEPRAAKAPRRTEKPAVGKAMV
KTWGKPKPGSRPKTKQK