Protein Info for Rru_A1302 in Rhodospirillum rubrum S1H

Annotation: Formiminoglutamate deiminase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 455 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details TIGR02022: formiminoglutamate deiminase" amino acids 2 to 454 (453 residues), 590 bits, see alignment E=1.5e-181 PF01979: Amidohydro_1" amino acids 50 to 430 (381 residues), 95.8 bits, see alignment E=3.3e-31 PF07969: Amidohydro_3" amino acids 93 to 396 (304 residues), 30.7 bits, see alignment E=2.5e-11

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 100% identity to rru:Rru_A1302)

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUU2 at UniProt or InterPro

Protein Sequence (455 amino acids)

>Rru_A1302 Formiminoglutamate deiminase (NCBI) (Rhodospirillum rubrum S1H)
MRNLFFQSLLLPEGWAENVAMTVDENGMIATLSPGSPPPASGPSFRGPAFAGIPNLHSHA
HQRALAGSGERSGGDGEDSFWSWRKAMYAALARLTPEAFEDVATQLYVEMVKAGYTAVAE
FHYLHHDRDGRPFADPAEMSHRLVAAARTAGIALTLLPVLYSASGFDGAPPTEGQKRFHT
TGSSFGALVERLKRDYGRDGAIMLGIAPHSLRAVPAPLLAEVIGAHPEGPIHLHIAEQTI
EVTDCLAHTGQRPVEWLLDHVDLDPRWCLIHATHVTDQELAGIAASRAVVGLCPTTEANL
GDGLFPADRFLGLGGRFGIGSDSHISVNPVEELRWLEYGQRLTTRRRTVLAGGIDRSTGR
ALIEQAQISGATACAIKAGRLAVGQRADIVVLDGEAPVLCGRSGDGALDAWIFSGNAPTV
HSVVVGGALVVENGRHRAEEAVARRFASTLGRLLA