Protein Info for Rru_A1296 in Rhodospirillum rubrum S1H

Annotation: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 52 to 75 (24 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 142 to 166 (25 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 9 to 107 (99 residues), 109.5 bits, see alignment E=4.9e-36 PF00528: BPD_transp_1" amino acids 35 to 213 (179 residues), 65.5 bits, see alignment E=2.7e-22

Best Hits

Swiss-Prot: 36% identical to YCKA_BACSU: Probable amino-acid ABC transporter permease protein YckA (yckA) from Bacillus subtilis (strain 168)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to rru:Rru_A1296)

MetaCyc: 38% identical to L-glutamine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-12-RXN [EC: 7.4.2.1]

Predicted SEED Role

"polar amino acid ABC transporter, inner membrane subunit"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RUU8 at UniProt or InterPro

Protein Sequence (218 amino acids)

>Rru_A1296 Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine (NCBI) (Rhodospirillum rubrum S1H)
MKFQVILANLPFLLKGAGSTIAISLVGILLGQVIGALVCVGRLSGNRLIDAIGALYVSFF
RGVPLLIQLLLIYYMLPLIGIDVPALMAAIGALGLASGAYVSEIYRGSLNAIPRGQGEAA
LALGFSGGSIWRRILLPQAFRLSVPALVNELILLLKASSLISVIGVAELTRVSQTVSAST
YRALEIYMAAGVIYFLINGCLAILGALVERHLRLQGRG