Protein Info for Rru_A1232 in Rhodospirillum rubrum S1H

Annotation: C-terminal processing peptidase S41A (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR00225: C-terminal processing peptidase" amino acids 52 to 376 (325 residues), 354.7 bits, see alignment E=2.4e-110 PF00595: PDZ" amino acids 97 to 167 (71 residues), 36.5 bits, see alignment E=1e-12 PF13180: PDZ_2" amino acids 99 to 172 (74 residues), 41.3 bits, see alignment E=3.1e-14 PF17820: PDZ_6" amino acids 114 to 168 (55 residues), 50 bits, see alignment 4.1e-17 PF03572: Peptidase_S41" amino acids 195 to 361 (167 residues), 205 bits, see alignment E=1.1e-64

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to rru:Rru_A1232)

Predicted SEED Role

"Carboxyl-terminal protease (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RV12 at UniProt or InterPro

Protein Sequence (440 amino acids)

>Rru_A1232 C-terminal processing peptidase S41A (NCBI) (Rhodospirillum rubrum S1H)
MTWKTWISASAIAFTAFTAGQLYHTEQAEAARGEETYQLLDLFADVFERVKRDYVEEVGD
DQLIEAAINGMLTSLDPHSSYLNAKHFEDMQVQTKGEFGGLGIEVTQEDGFIKVVSPIDE
TPAALAGLQPGDFITHLDGESVLGLSLADAVEKMRGPVGKEIRLTIQRVGKEPFDVTLKR
DTIKIQSVKSRMEGDVGYVRITSFSEQTEKSLREALDDLRSKGGDSIKGYVLDLRNNPGG
LLEQAIAVSDVFLDKGEIVSTRARDAKDTQRFNARPGDLTKGMPVVVLINSGSASASEIV
AGALQDHHRALIVGTKSFGKGSVQTIMPLPGHGAMRLTTARYYTPSGRSIQALGIDPDIQ
VEPARIEAISAQNEMRSEAELRNALKNDTLKPSLGVKPANGLPPSQVRNDQTPQADTDYQ
LARAVDLIRGLAIYRSKSIQ