Protein Info for Rru_A1218 in Rhodospirillum rubrum S1H

Annotation: phage shock protein A, PspA (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 TIGR02977: phage shock protein A" amino acids 1 to 220 (220 residues), 292.1 bits, see alignment E=1.4e-91 PF04012: PspA_IM30" amino acids 2 to 217 (216 residues), 145.9 bits, see alignment E=7e-47

Best Hits

Swiss-Prot: 50% identical to PSPA_ECOLI: Phage shock protein A (pspA) from Escherichia coli (strain K12)

KEGG orthology group: K03969, phage shock protein A (inferred from 100% identity to rru:Rru_A1218)

Predicted SEED Role

"Phage shock protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RV26 at UniProt or InterPro

Protein Sequence (226 amino acids)

>Rru_A1218 phage shock protein A, PspA (NCBI) (Rhodospirillum rubrum S1H)
MGIFSRLTDIVNANLNSLIDRAEDPEKMARLMIQEMEDTLVEVRTATVRTIADRKDLERS
LERLEAGGREWGEKAEFALAKGREDLAKAALIAKRKLADQAEGARAELKAIDESLAKTNV
DLGQLQAKLEEAKAKRKSLEIRMRSAQKRVDLRRTLHDGRIDEALGRYDSLERRISELEA
DAESYDLGKTAGVSLDEQFSELRAEADVEDELARLKETVARRGAGA