Protein Info for Rru_A1016 in Rhodospirillum rubrum S1H

Annotation: Binding-protein-dependent transport systems inner membrane component (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 40 to 64 (25 residues), see Phobius details amino acids 106 to 132 (27 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 195 to 217 (23 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 294 to 315 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 125 to 313 (189 residues), 59.6 bits, see alignment E=1.8e-20

Best Hits

Swiss-Prot: 60% identical to POTH_ECOLI: Putrescine transport system permease protein PotH (potH) from Escherichia coli (strain K12)

KEGG orthology group: K11075, putrescine transport system permease protein (inferred from 100% identity to rru:Rru_A1016)

MetaCyc: 60% identical to putrescine ABC transporter membrane subunit PotH (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotH (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVM8 at UniProt or InterPro

Protein Sequence (330 amino acids)

>Rru_A1016 Binding-protein-dependent transport systems inner membrane component (NCBI) (Rhodospirillum rubrum S1H)
MTAEPAPGAAPVSRPPEILPGMAPWRMWLDAQIRHNGRRLVILVPYVWLLLFFVLPFAIV
LKISFAEFRVGVPPYTALIDFTQDAYLRLTLALSNYKYMLDDEMYVIAYLNSLRIAGIST
VLALLIGYPMAYGIARAPKGPRTILLFLVILPFWTSFLIRVYAWMGILKGNGLLNTFLIW
TGVIDQPLTIMGTEWAVFIGIVYSYLPFMVLPLYATLEKLDPSLLEAAHDLGCRPWKAFL
TITLPLSVPGIIAGSMLVFIPSVGEFVIPELLGGADTFMIGRVLWNEFFLNRDWPVASAV
AVAMLLMLVVPIMIFQNIQAKQAEAAEERS