Protein Info for Rru_A1003 in Rhodospirillum rubrum S1H

Annotation: Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 26 to 45 (20 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 91 to 117 (27 residues), see Phobius details amino acids 129 to 151 (23 residues), see Phobius details amino acids 186 to 205 (20 residues), see Phobius details amino acids 225 to 246 (22 residues), see Phobius details amino acids 266 to 285 (20 residues), see Phobius details amino acids 340 to 356 (17 residues), see Phobius details amino acids 367 to 389 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 89 to 152 (64 residues), 56.6 bits, see alignment E=1.5e-19 PF00528: BPD_transp_1" amino acids 229 to 393 (165 residues), 48.6 bits, see alignment E=4.1e-17

Best Hits

Swiss-Prot: 58% identical to YHDX_ECOLI: Putative amino-acid ABC transporter permease protein YhdX (yhdX) from Escherichia coli (strain K12)

KEGG orthology group: K09970, general L-amino acid transport system permease protein (inferred from 100% identity to rru:Rru_A1003)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVP1 at UniProt or InterPro

Protein Sequence (398 amino acids)

>Rru_A1003 Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine (NCBI) (Rhodospirillum rubrum S1H)
MTPPIHPPGPLKAPRPHPLRDPRVRAIAFQVLTIAALVWFFWAIFDNTLTNMRTRGITTG
FAFLDHSAGFGILMSLIPYDETYSYGRTFVVGLLNTLLVSGLGVIAATLIGFVVGVARLS
RNWLIAKLALIYVETLRNIPLLLQIFFWYFAVLRPLPQPRQSLELGALFFLNNRGFYMPS
PIAGDGMALVGLALVVALALALAIGRWATRRRMATGLGFPSWRTGLALVLGLPLLAFLAL
GTPVTFDVPHLQGFNFVGGSRLIPEMVALLLALSMYTAAFIAEIVRSGILAVSHGQTEAA
HSLGLKPTATLRLIVLPQALRVMIPPTTSQYLNLIKNSSLATAIGYPDLVSVFMGTTLNQ
TGQAVEIVGMTMAVYLLISLVVSGLMNWYNRAVALKER