Protein Info for Rru_A0950 in Rhodospirillum rubrum S1H

Annotation: N-acetylglucosaminyltransferase, MurG (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details TIGR01133: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase" amino acids 18 to 368 (351 residues), 272.5 bits, see alignment E=2.6e-85 PF03033: Glyco_transf_28" amino acids 19 to 153 (135 residues), 101.9 bits, see alignment E=4.9e-33 PF04101: Glyco_tran_28_C" amino acids 199 to 364 (166 residues), 121.3 bits, see alignment E=6.5e-39

Best Hits

Swiss-Prot: 100% identical to MURG_RHORT: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K02563, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC: 2.4.1.227] (inferred from 100% identity to rru:Rru_A0950)

Predicted SEED Role

"UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227)" in subsystem Peptidoglycan Biosynthesis (EC 2.4.1.227)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.227

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVU4 at UniProt or InterPro

Protein Sequence (387 amino acids)

>Rru_A0950 N-acetylglucosaminyltransferase, MurG (NCBI) (Rhodospirillum rubrum S1H)
MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGG
TLGLLDTKRILAGGVAGRGVIGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPT
MLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFARAERPRGARPVVVGMPVRPSV
LALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPED
IEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPH
AIDDHQTANARGLDEVGGGWLMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPD
AAVRLADLVSATADHRVPEMPPKEISA