Protein Info for Rru_A0945 in Rhodospirillum rubrum S1H

Annotation: Cell division protein FtsA (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 TIGR01174: cell division protein FtsA" amino acids 34 to 405 (372 residues), 364.9 bits, see alignment E=2.4e-113 PF14450: FtsA" amino acids 36 to 219 (184 residues), 34.5 bits, see alignment E=6.2e-12 amino acids 232 to 401 (170 residues), 120.6 bits, see alignment E=1.4e-38 PF02491: SHS2_FTSA" amino acids 109 to 185 (77 residues), 68.3 bits, see alignment E=1.5e-22 PF06277: EutA" amino acids 222 to 276 (55 residues), 29.2 bits, see alignment 1.2e-10 PF06723: MreB_Mbl" amino acids 222 to 369 (148 residues), 37.1 bits, see alignment E=4.2e-13

Best Hits

Swiss-Prot: 46% identical to FTSA_RHIME: Cell division protein FtsA (ftsA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K03590, cell division protein FtsA (inferred from 100% identity to rru:Rru_A0945)

Predicted SEED Role

"Cell division protein FtsA" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RVU9 at UniProt or InterPro

Protein Sequence (440 amino acids)

>Rru_A0945 Cell division protein FtsA (NCBI) (Rhodospirillum rubrum S1H)
MPRDAISKDTPTAARTRRKDHRAAPPRRQRGGLITALDVGTTKIACFIAREEEDGALRVL
GVGHHRSRGMRNGQVANMDEVELSVRAAVDAAEQMANERISSVVVNVSGGQPHSTRVEVE
MSIAGHEVRGNDVRRIQAYGRGLHTSADRELVHCIPVSYAIDGTEGVLDPRGMFGQSLGV
SIHLVSAAAGPLRNLSTVVERCHLDIEDKVVSPYASGLACLVEDEKQMGVTVIDLGGGTT
SIAVFHEGHVVHTEMIPVGGLHVTNDIAKGLTTPVANAERLKTIHGSCSVSPADTREILR
VPLVGEDDEATANEVPRSMLVQIIRPRIEETFELVRGRLEASGFDKVGGRLVVLTGGGSQ
LQGVRELAEVILDRQVRPGRPQRIRGLADSTSGPAFATCAGMLRYAVQHQVETPDTDPTA
DETVATGALGRFARWWKDNF