Protein Info for Rru_A0833 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF48 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 344 transmembrane" amino acids 46 to 70 (25 residues), see Phobius details TIGR03640: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG" amino acids 3 to 343 (341 residues), 511.7 bits, see alignment E=9.7e-158 TIGR00287: CRISPR-associated endonuclease Cas1" amino acids 7 to 339 (333 residues), 269.7 bits, see alignment E=3.4e-84 PF01867: Cas_Cas1" amino acids 8 to 299 (292 residues), 339 bits, see alignment E=1e-105

Best Hits

Swiss-Prot: 100% identical to CAS1B_RHORT: CRISPR-associated endonuclease Cas1 2 (cas1-2) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: None (inferred from 100% identity to rru:Rru_A0833)

Predicted SEED Role

"CRISPR-associated protein Cas1" in subsystem CRISPRs

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RW61 at UniProt or InterPro

Protein Sequence (344 amino acids)

>Rru_A0833 Protein of unknown function DUF48 (NCBI) (Rhodospirillum rubrum S1H)
MKKLLNTVYVTTEGTGLRKDGENLVAELDGVQKGRVPLHMVGSVVVFGGTYVSPGLMGAC
AAHGITIVLLDRVGRFQARVEGPVAGNVLLRRAQYKASEAPEDIVKSLILGKVSNQRAVL
LRALRDHGADFPAAEALAVKDAIDRMAHILRKVGASAEDADHLRGAEGEAASLYFGVFGQ
LIRSPDGDFAFRGRSRRPPLDPTNALLSFLYTLLTHDCRSACESVGLDPAVGFLHRDRPG
RPSLALDLMEELRPVLVDRLALSLINRRQLRATDFQRLDGGAVLLTDEARKTVLSAWQER
KKQERRHPFLEESAPLGLVPYLQAQMLARHLRGDLDAYPPWFWK