Protein Info for Rru_A0832 in Rhodospirillum rubrum S1H

Annotation: Protein of unknown function DUF83 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 228 TIGR00372: CRISPR-associated protein Cas4" amino acids 18 to 200 (183 residues), 113 bits, see alignment E=7.3e-37 PF01930: Cas_Cas4" amino acids 21 to 200 (180 residues), 68.6 bits, see alignment E=7.1e-23

Best Hits

KEGG orthology group: K07464, putative RecB family exonuclease (inferred from 100% identity to rru:Rru_A0832)

Predicted SEED Role

"CRISPR-associated RecB family exonuclease Cas4"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RW62 at UniProt or InterPro

Protein Sequence (228 amino acids)

>Rru_A0832 Protein of unknown function DUF83 (NCBI) (Rhodospirillum rubrum S1H)
MAEGDQPKDEAGWQGEPIPLSALQHAVYCLRQAALIHLERLWEENRFTAEGHVLHITADK
MGGRKIRGTRRVMALPLAAKSLGIAGVGDLVEFRGEADGTETPYPVEYKRGKAKLHPADE
VQLCAQGLCLEEMTGQAVPEGALYYGETKRRVVVPFDPPLRDLTVRTIEELRGVFTTLKT
PPALFRADRCRGCSLIDLCRPKATAKPARSWRQRTLASLLSDEEGTGA