Protein Info for Rru_A0794 in Rhodospirillum rubrum S1H

Annotation: Nitrogenase (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 PF00148: Oxidored_nitro" amino acids 76 to 468 (393 residues), 255.3 bits, see alignment E=4.7e-80

Best Hits

KEGG orthology group: K02586, nitrogenase molybdenum-iron protein alpha chain [EC: 1.18.6.1] (inferred from 100% identity to rru:Rru_A0794)

MetaCyc: 100% identical to methylthio-alkane reductase catalytic subunit alpha (Rhodospirillum rubrum)

Predicted SEED Role

"Nitrogenase (molybdenum-iron) alpha chain (EC 1.18.6.1)" in subsystem Nitrogen fixation (EC 1.18.6.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.18.6.1

Use Curated BLAST to search for 1.18.6.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RW97 at UniProt or InterPro

Protein Sequence (511 amino acids)

>Rru_A0794 Nitrogenase (NCBI) (Rhodospirillum rubrum S1H)
MPINLKTSVVESREQRLGTIIAWDGKASDLSKESAYARSEGCGSACGAKARRVCEMRSPF
SQGSVCSEQMVECQAGNVRGAVLVQHSPIGCGAGQVIYNSIFRNGLAIRGLPVENLHLIS
TNLRERDMVYGGLDKLERTIRDAWERHHPQAIFIATSCPTAIIGDDIESVASQLEAEFGI
PVIPLHCEGFKSKHWSTGFDATQHGILRQIVRKNPERKQEDLVNVINLWGSDVFGPMLGE
LGLRVNYVVDLATVEDLAQMSEAAATVGFCYTLSTYMAAALEQEFGVPEVKAPMPYGFAG
TDAWLREIARVTHREEQAEAYIAREHARVKPQLEALREKLKGIKGFVSTGSAYAHGMIQV
LRELGVTVDGSLVFHHDPVYDSQDPRQDSLAHLVDNYGDVGHFSVGNRQQFQFYGLLQRV
KPDFIIIRHNGLAPLASRLGIPAIPLGDEHIAVGYQGILNLGESILDVLAHRKFHEDIAA
HVRLPYRQDWLARDPFDLARQSAGQPRRPAE