Protein Info for Rru_A0769 in Rhodospirillum rubrum S1H

Annotation: extracellular solute-binding protein, family 1 (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 347 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF01547: SBP_bac_1" amino acids 41 to 287 (247 residues), 48.3 bits, see alignment E=3e-16 PF13531: SBP_bac_11" amino acids 43 to 291 (249 residues), 49.6 bits, see alignment E=9.4e-17 PF13416: SBP_bac_8" amino acids 46 to 316 (271 residues), 68.3 bits, see alignment E=2e-22 PF13343: SBP_bac_6" amino acids 78 to 303 (226 residues), 55.5 bits, see alignment E=1.2e-18

Best Hits

Swiss-Prot: 43% identical to FUTA1_SYNY3: Iron uptake protein A1 (futA1) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 100% identity to rru:Rru_A0769)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWC2 at UniProt or InterPro

Protein Sequence (347 amino acids)

>Rru_A0769 extracellular solute-binding protein, family 1 (NCBI) (Rhodospirillum rubrum S1H)
MSFARPRLFPVLISLLAGSTSLAGPAMAEGEVNIYSYRQPFLIQPMLDRFTAETGVRTNV
VFTDQGLVERLKAEGANSPADVVLTVDISRLNELVTAKVVRPVSSPVIEANIPAATRDPQ
GRWFGLTTRARAIFAAKDRVPAGAVTSYADLADPRWKGRVCSRPGDHVYNIGLISAMIAH
DGVDKTKAWLEGVKANLAQKPGGSDRSQVKAIKEGLCDLALVNTYYLGAMLADPDQKAWA
ESATMLFPDLSGHGTHVNVSGMAMTASAPNRDNALKLMEFLSGDEAQRLYAEANSEFPVK
PDVARSPLVASWGTFTADPIALTEVASRAGEALKLVNEVDFNEGPGS