Protein Info for Rru_A0753 in Rhodospirillum rubrum S1H

Annotation: Chaperone clpB (NCBI)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 870 TIGR03346: ATP-dependent chaperone protein ClpB" amino acids 6 to 859 (854 residues), 1420.6 bits, see alignment E=0 PF02861: Clp_N" amino acids 17 to 68 (52 residues), 53.5 bits, see alignment 1.4e-17 amino acids 96 to 144 (49 residues), 39.6 bits, see alignment 3e-13 PF00004: AAA" amino acids 203 to 315 (113 residues), 39.8 bits, see alignment E=3.9e-13 amino acids 606 to 723 (118 residues), 30.8 bits, see alignment E=2.5e-10 PF17871: AAA_lid_9" amino acids 344 to 444 (101 residues), 122.4 bits, see alignment E=4.8e-39 PF07724: AAA_2" amino acids 600 to 764 (165 residues), 231.3 bits, see alignment E=4.5e-72 PF00158: Sigma54_activat" amino acids 603 to 714 (112 residues), 22.7 bits, see alignment E=4.6e-08 PF07728: AAA_5" amino acids 605 to 723 (119 residues), 49 bits, see alignment E=4.4e-16 PF10431: ClpB_D2-small" amino acids 771 to 850 (80 residues), 102.1 bits, see alignment E=9e-33

Best Hits

Swiss-Prot: 71% identical to CLPB_RHOPA: Chaperone protein ClpB (clpB) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)

KEGG orthology group: K03695, ATP-dependent Clp protease ATP-binding subunit ClpB (inferred from 70% identity to bja:blr1404)

MetaCyc: 61% identical to protein disaggregase ClpB (Escherichia coli K-12 substr. MG1655)
RXN185E-10

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q2RWD8 at UniProt or InterPro

Protein Sequence (870 amino acids)

>Rru_A0753 Chaperone clpB (NCBI) (Rhodospirillum rubrum S1H)
MDPEKLTDRSKGFLQAAQTIALRETHQQVTPEHLLKALLDDKEGLAANLIRAAGGDPLRA
QEAVNREVDKLPKVQGAQQMYWAQSLARVIDQATRMAEKAGDSFVTVERLLIALAMAAET
PAKRILAEAGATPQGLNKAVEDLRKGRKADSAGAESQYDALKKYARDLTEAAREGKLDPV
IGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIIEGLALRIVNGDVPESLQNKKLMAL
DLGAMVAGAKFRGEFEERLKAMLTEVSAAEGEIILFIDEMHTLIGAGAGEGAMDASNLLK
PALARGDLHCVGATTLNEYRKHVEKDAALARRFQPVFVSEPGVADTISILRGIKEKYELH
HGVRIADNALVAAATLSNRYITDRFLPDKAIDLMDEAASRLRMEVDSKPEALDELDRRII
QLKIEREALRKEKDIASEARLSDLEKELADLESQSATLTEDWKREKEGLAGSTRIKEQLE
QARGDLDIAKRQANWARAGELEYGVIPDLERRLGEVESGDGLAHRQGGKLVNEVVTAETI
ASVVSRWTGIPVDKMLAGEREKLLGMEKVLASRVVGQREAVVAVSNAVRRSRAGLQDPNR
PMGSFLFLGPTGVGKTELTKALAAFLFDDEQAMVRIDMSEYMEKHAVSRLIGAPPGYVGY
DEGGALTEAVRRRPYQVILFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIVL
TSNLGADILANQPEGDDSGAVRGAVMEMVRAAFRPEFLNRLDEILLFHRLFRENMAGIVS
IQLGRLADRLRDRKMTLDLDDAARDWLAERGYDPVYGARPLKRVIQRSLENPLATLVLDG
RIKDGDVIRITVEGGKLVVNGEALSLDTAA